Volume 538 Issue 7624


Healing the traumatized minds of refugees p.139

Host countries need to deal with the raised levels of mental-health disorders in migrants if they expect them to integrate well, and that could mean benefits for psychological care in rich countries too.

doi: 10.1038/538139a


News Features

News & Views

Megafloods downsized p.174

A fresh look at the Channeled Scablands of North America shows that the ancient floods that scarred that landscape were smaller than is commonly assumed. This result could revise estimates of similar floods on Mars. See Letter p.229

doi: 10.1038/538174a

Measuring our narrow strip of life p.175

In line with previous research, a demographic analysis corroborates the presence of a limit to human lifespan, indicating that increases in life expectancy are likely to slow down or stop over the coming years.

doi: 10.1038/nature19475

Fifty years of C4 photosynthesis p.177

Half a century after the discovery of a plant photosynthetic pathway termed C4, researchers are working to engineer this efficient pathway into crops such as rice to maintain food security.

doi: 10.1038/538177b

A map of human wanderlust p.179

Genetic studies of individuals from geographically diverse human populations provide insights into the dispersal of modern humans across the globe and how geography shaped genomic variation. See Articles p.201 & p.207 & Letter p.238

doi: 10.1038/nature19472

Lethal violence deep in the human lineage p.180

Researchers estimate that the incidence of human lethal violence at the time of the origin of our species was about six times higher than for the average mammal, but about as violent as expected, given our great-ape ancestry. See Letter p.233

doi: 10.1038/nature19474


In vitro and ex vivo strategies for intracellular delivery p.183

Intracellular delivery methods, which are critical to both fundamental research applications and cell-based therapies, are reviewed, concentrating on membrane-disruption-based methods and the use of nanotechnology, microfluidics and laboratory-on-chip technology.

doi: 10.1038/nature19764


The Simons Genome Diversity Project: 300 genomes from 142 diverse populations p.201

Deep whole-genome sequencing of 300 individuals from 142 diverse populations provides insights into key population genetic parameters, shows that all modern human ancestry outside of Africa including in Australasians is consistent with descending from a single founding population, and suggests a higher rate of accumulation of mutations in non-Africans compared to Africans since divergence.

doi: 10.1038/nature18964

A genomic history of Aboriginal Australia p.207

Whole-genome sequence data for 108 individuals representing 28 language groups across Australia and five language groups for Papua New Guinea suggests that Aboriginal Australians and Papuans diverged from Eurasian populations approximately 60–100 thousand years ago, following a single out-of-Africa dispersal and subsequent admixture with archaic populations.

doi: 10.1038/nature18299


Enhanced flexoelectric-like response in oxide semiconductors p.219

Semiconducting single crystals of doped barium titanate and titanium dioxide exhibit a flexoelectric-like response upon bending that is much larger than in their undoped, insulating counterparts, reaching unprecedentedly large effective flexoelectric coefficients.

doi: 10.1038/nature19761

Evolution of global temperature over the past two million years p.226

Reconstruction of global average surface temperature for the past two million years shows continuous cooling until about 1.2 million years ago, followed by a general flattening, with close coupling of global temperature and atmospheric greenhouse gas concentrations over the past 800,000 years.

doi: 10.1038/nature19798

The phylogenetic roots of human lethal violence p.233

The percentage of human deaths caused by interpersonal violence reflects our membership of a particularly violent clade of mammals, although changes in socio-political organization have led to marked variations in this proportion.

doi: 10.1038/nature19758

De novo assembly and phasing of a Korean human genome OPEN p.243

De novo assembly and phasing of the genome of an individual from Korea using a combination of different sequencing approaches provides a useful population-specific reference genome and represents the most contiguous human genome assembly so far.

doi: 10.1038/nature20098