Volume 538 Number 7623

Editorials

News

News Features

News & Views

Cobalt gets in shape p.44

Solid cobalt-based catalysts are used commercially to convert carbon monoxide and hydrogen into synthetic fuels. It emerges that much more valuable chemicals can be produced by using a different form of cobalt catalyst. See Letter p.84

doi: 10.1038/538044a

Acidic shield puts a chink in p53's armour p.45

Underactivity of the transcription factor p53 can lead to tumour development. The discovery that the SET protein binds to and inhibits p53 points to a way to unleash the tumour suppressor's activity. See Letter p.118

doi: 10.1038/nature19469

Rebalancing the global methane budget p.46

A database of the carbon-isotope 'fingerprints' of methane has been used to constrain the contributions of different sources to the global methane budget. The surprising results have implications for climate prediction. See Letter p.88

doi: 10.1038/538046a

Search for neutrinoless double-β decay p.48

Neutrinos are much lighter than the other constituents of matter. One explanation for this could be that neutrinos are their own antiparticles and belong to a new class of 'Majorana' particle. An experiment sets strong constraints on this scenario.

doi: 10.1038/nature19473

Climate and the peopling of the world p.49

The human dispersal out of Africa that populated the world was probably paced by climate changes. This is the inference drawn from computer modelling of climate variability during the time of early human migration. See Letter p.92

doi: 10.1038/nature19471

Review

Circuit-based interrogation of sleep control p.51

Weber and Dan review our understanding of the neural circuits controlling sleep, focusing on the advances in measurement and manipulation of neuronal activity and circuit tracing from genetically defined cell types.

doi: 10.1038/nature19773

Articles

Letters

Nodal-chain metals p.75

A hitherto unrecognized type of fermionic excitation in metals is described, which forms a chain of connected loops in momentum space (a nodal chain) along which conduction and valence bands touch.

doi: 10.1038/nature19099

A cross-modal genetic framework for the development and plasticity of sensory pathways p.96

In the neocortex, sensory information flows into areas specific for a particular modality through parallel thalamocortical circuits, consisting of first order and higher order nuclei connecting to primary and secondary cortical areas, respectively; here, the authors identify common developmental genetic programs that organize these conserved features in parallel sensory pathways.

doi: 10.1038/nature19770