Study suggests new treatments for jaw tumors
Nature Genetics
2014년5월26일
Two genes linked to ameloblastomas, tumors of the jaw, are reported in a paper published online this week in Nature Genetics. The results suggest promising treatment options for these destructive jaw tumors.
Ameloblastomas are rare, benign tumors that often lead to facial disfigurement. Robert West and colleagues identified two genes, SMO and BRAF, that are often mutated in ameloblastomas. In their samples, tumors of the upper jaw tended to have SMO mutations, whereas the lower jaw tumors tended to have BRAF mutations. For each gene, the researchers identified an FDA-approved drug that can inhibit the mutant form in human cells. More testing is needed to see if these drugs can help ameloblastoma patients.
doi: 10.1038/ng.2986
리서치 하이라이트
-
7월1일
Criminology: Predicting police enforcement bias in major US citiesNature Human Behaviour
-
7월1일
Space health: The path of most resistance could help limit bone loss during spaceflightScientific Reports
-
6월30일
Microbiology: Transmission of gastrointestinal viruses in salivaNature
-
6월29일
COVID-19: Assessing instances of long COVID in UK health dataNature Communications
-
6월24일
Sport science: New wearable sensor to measure neck strain may detect potential concussionScientific Reports
-
6월23일
Scientific community: Women credited less than men in scientific paper authorshipNature