Lower emissions on the high seas p.5

Global regulations to limit carbon dioxide from the shipping industry are overdue.

doi: 10.1038/551005b

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Frédéric Chopin’s telltale heart p.5

Scientists have written another chapter in the curious case of the composer’s heart. But it is unlikely to be the end of the story.

doi: 10.1038/551005a

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Citation is not the only impact p.6

A look at what we have published highlights the variety of editorial judgements in selecting and assessing papers.

doi: 10.1038/551006a

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Ageing satellites put crucial sea-ice climate record at risk​ p.13

Scientists scramble to avert disruption to data set that has tracked polar ice since the late 1970s.

doi: 10.1038/nature.2017.22907

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Plans to promote German research excellence come under fire p.15

Critics say selection process for high-stakes funding programme is flawed.

doi: 10.1038/551015a

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Geneticists are starting to unravel evolution's role in mental illness p.15

Hints emerge that past environments could have influenced psychiatric disorders.

doi: 10.1038/nature.2017.22914

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US March for Science group faces growing pains p.16

A group of volunteers claims that the organization that spearheaded global protests in April has been unduly secretive about its management practices.

doi: 10.1038/nature.2017.22909

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Camouflage plumage patterns offer clue to dinosaur’s habitat p.17

Feathered carnivore was dark on top and light underneath, with a raccoon-like face.

doi: 10.1038/nature.2017.22891

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Genomic studies track early hints of cancer p.18

Pilot projects aim to pinpoint how benign tumours turn into lung, breast, prostate and pancreatic cancers.

doi: 10.1038/nature.2017.22911

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News Features


The new thermodynamics: how quantum physics is bending the rules p.20


doi: 10.1038/551020a

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News & Views


Gravitational waves: A golden binary p.36


doi: 10.1038/nature24153

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Biochemistry: The surprising history of an antioxidant p.37


doi: 10.1038/551037a

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Chromosome biology: How to build a cohesive genome in 3D p.38


doi: 10.1038/nature24145

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Theoretical physics: Quarks fuse to release energy p.40


doi: 10.1038/551040a

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Neurobiology: A change of fate for nerve repair p.41


doi: 10.1038/551041a

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Molecular evolution: No escape from the tangled bank p.42


doi: 10.1038/nature24152

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The dynamics of molecular evolution over 60,000 generations p.45

Using data from sixty thousand generations of the E. coli long-term evolution experiment, the authors shed new light on the processes that govern molecular evolution.

doi: 10.1038/nature24287

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Two independent modes of chromatin organization revealed by cohesin removal p.51

Depletion of chromosome-associated cohesin leads to loss of topologically associating domains in interphase chromosomes, without affecting segregation into compartments, and instead, it unmasks a finer compartment structure that reflects local chromatin and transcriptional activity.

doi: 10.1038/nature24281

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構造生物学:紅藻のGriffithsia pacificaに由来するフィコビリソームの構造

Structure of phycobilisome from the red alga Griffithsia pacifica p.57

Single-particle cryo-electron microscopy is used to resolve the structure of the phycobilisome, a 16.8-megadalton light-harvesting megacomplex, from the red alga Griffithsia pacifica at a resolution of 3.5 Å.

doi: 10.1038/nature24278

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Optical emission from a kilonova following a gravitational-wave-detected neutron-star merger p.64

Optical to near-infrared observations of a transient coincident with the detection of the gravitational-wave signature of a binary neutron-star merger and a low-luminosity short-duration γ-ray burst are presented and modelled.

doi: 10.1038/nature24291

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Spectroscopic identification of r-process nucleosynthesis in a double neutron-star merger p.67

Observations of the transient associated with the gravitational-wave event GW170817 and γ-ray burst GRB 170817A reveal a bright kilonova with fast-moving ejecta, including lanthanides synthesized by rapid neutron capture.

doi: 10.1038/nature24298

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The X-ray counterpart to the gravitational-wave event GW170817 p.71

Detection of X-ray emission at a location coincident with the kilonova transient of the gravitational-wave event GW170817 provides the missing observational link between short γ-ray bursts and gravitational waves from neutron-star mergers.

doi: 10.1038/nature24290

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A kilonova as the electromagnetic counterpart to a gravitational-wave source p.75

Observations and modelling of an optical transient counterpart to a gravitational-wave event and γ-ray burst reveal that neutron-star mergers produce gravitational waves and radioactively powered kilonovae, and are a source of heavy elements.

doi: 10.1038/nature24303

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Origin of the heavy elements in binary neutron-star mergers from a gravitational-wave event p.80

Modelling the electromagnetic emission of kilonovae enables the mass, velocity and composition (with some heavy elements) of the ejecta from a neutron-star merger to be derived from the observations.

doi: 10.1038/nature24453

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A gravitational-wave standard siren measurement of the Hubble constant p.85

The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

doi: 10.1038/nature24471

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Quark-level analogue of nuclear fusion with doubly heavy baryons p.89

Two singly charmed baryons can fuse into the recently discovered doubly charmed baryon and a neutron through an exothermic reaction analogous to the nuclear fusion between deuterium and tritium.

doi: 10.1038/nature24289

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Association analysis identifies 65 new breast cancer risk loci p.92

Association analysis identifies 65 new breast cancer risk loci, predicts target genes for known risk loci and demonstrates a strong overlap with somatic driver genes in breast tumours.

doi: 10.1038/nature24284

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Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites p.95

Highly parallel single-cell transcriptome profiling of Plasmodium falciparum blood stages provides insight into the role AP2-G plays in early sexual development of this eukaryotic pathogen.

doi: 10.1038/nature24280

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Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte p.100

Single-cell transcriptomics analyses of cell intermediates during the reprogramming from fibroblast to cardiomyocyte were used to reconstruct the reprogramming trajectory and to uncover intermediate cell populations, gene pathways and regulators involved in this process.

doi: 10.1038/nature24454

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Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation p.105

TGFβ signalling regulates T helper 17 (TH17) cell differentiation by reversing SKI–SMAD4-mediated suppression of RORγt, revealing a potential therapeutic target for treating TH17-related diseases.

doi: 10.1038/nature24283

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IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity p.110

Interleukin-1 receptor 8 (IL-1R8), a negative regulator of the IL-1 family of cytokines, restrains the activity of natural killer (NK) cells, suggesting that IL-1R8 acts as a checkpoint regulator of NK cell activation and that its blockade may be of use in cancer therapy.

doi: 10.1038/nature24293

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Glucose feeds the TCA cycle via circulating lactate p.115

Metabolic flux analysis in mice reveals that lactate often acts as the primary carbon source for the tricarboxylic acid cycle both in normal tissues and in tumour microenvironments.

doi: 10.1038/nature24057

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A global resource allocation strategy governs growth transition kinetics of Escherichia coli p.119

A new approach to modelling bacterial growth removes the need to know kinetic parameters for metabolic and regulatory processes and can be used to model adaptive processes such as antibiotic responses and ecological dynamics.

doi: 10.1038/nature24299

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Embryonic epigenetic reprogramming by a pioneer transcription factor in plants p.124

The seed-specific transcription factor LEC1 promotes an active chromatin state at the floral repressor FLC and activates its expression in the Arabidopsis pro-embryo, thus reversing the winter cold-induced silenced state that is inherited from gametes.

doi: 10.1038/nature24300

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