Merkel deserves another term as German chancellor p.5

The former physicist shows a welcome immunity to the mood of anti-science resentment that has infected some democracies.

doi: 10.1038/549005a

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Removing statues of historical figures risks whitewashing history p.5

Science must acknowledge mistakes as it marks its past.

doi: 10.1038/549005b

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Cuckoo call adds another layer of deception p.6

The female bird makes a different and much sneakier sound than the male.

doi: 10.1038/549006a

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How labs are coping with Hurricane Harvey's devastating floods p.13

Advance planning has kept some Texas facilities safe during the unprecedented storm.

doi: 10.1038/nature.2017.22542

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Skeleton plundered from Mexican cave was one of the Americas’ oldest p.14

Rock-encased bone shard left behind by thieves allowed researchers to determine that the remains are probably more than 13,000 years old.

doi: 10.1038/nature.2017.22521

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Massive Ebola data site planned to combat outbreaks p.15

An international partnership seeks African leadership to organize information about the disease.

doi: 10.1038/nature.2017.22545

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Artificial warming trial reveals striking sea-floor changes p.16

Researchers deliberately heated up a slice of the Antarctic sea bed to see how ecosystems responded.

doi: 10.1038/nature.2017.22543

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Budget battle looms for US science programmes p.17

Competing spending priorities in the House of Representative and Senate could push funding negotiations into December.

doi: 10.1038/nature.2017.22548

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News Features


The secret to Germany’s scientific excellence p.18


doi: 10.1038/549018a

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News & Views


Surface science: Catalytic hotspots get noisy p.34


doi: 10.1038/549034a

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Plant science: Sexual attraction channelled in moss p.35

今回、ヒメツリガネゴケ(Physcomitrella patens)の有性生殖と初期胚発生の両方が、イオンチャネルタンパク質を通した細胞へのカルシウムの流入によって制御されていることが、遺伝子解析から明らかになった。

doi: 10.1038/nature23543

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Materials science: Pulley protection in batteries p.37


doi: 10.1038/549037a

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Molecular biology: Rhino gives voice to silent chromatin p.38


doi: 10.1038/549038a

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Cancer models: The next best thing p.39


doi: 10.1038/nature23545

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Applied physics: Quantum signals could soon span the globe p.41


doi: 10.1038/549041a

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Satellite-to-ground quantum key distribution p.43

Decoy-state quantum key distribution from a satellite to a ground station is achieved with much greater efficiency than is possible over the same distance using optical fibres.

doi: 10.1038/nature23655

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Commensal bacteria make GPCR ligands that mimic human signalling molecules p.48

Commensal bacteria have N-acyl amide synthase genes that encode signalling molecules (N-acyl amides) that can interact with G-protein-coupled receptors and elicit host cellular responses similar to eukaryotic N-acyl amides.

doi: 10.1038/nature23874

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A heterochromatin-dependent transcription machinery drives piRNA expression p.54

Transcription of Drosophila PIWI-interacting RNA (piRNA) clusters is enforced through RNA polymerase II pre-initiation complex formation within repressive heterochromatin, accomplished through the transcription factor IIA subunit paralogue Moonshiner.

doi: 10.1038/nature23482

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Channel opening and gating mechanism in AMPA-subtype glutamate receptors p.60

The structures of AMPA receptors in complex with auxiliary proteins are resolved by cryo-electron microscopy, and reveal conformational and permeation pathway changes that are associated with activation and desensitization of ionotropic glutamate receptors.

doi: 10.1038/nature23479

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Discrete and broadband electron acceleration in Jupiter’s powerful aurora p.66

The process that generates Earth’s most intense aurora is found to occur at Jupiter, but is of only secondary importance in generating Jupiter’s much more powerful aurora.

doi: 10.1038/nature23648

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Ground-to-satellite quantum teleportation p.70

Quantum teleportation of single-photon qubits from a ground observatory to a satellite in low-Earth orbit via an uplink channel is achieved with a fidelity that is well above the classical limit.

doi: 10.1038/nature23675

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Direct instrumental identification of catalytically active surface sites p.74

Scanning tunnelling microscopy is used to distinguish between different active sites of a catalyst—such as boundaries between different materials—during a reaction, allowing the contributions of these sites to be evaluated.

doi: 10.1038/nature23661

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A series of energetic metal pentazolate hydrates p.78

Metal complexes of the pentazole anion exhibit multiple coordination modes, through ionic, covalent and hydrogen-bonding interactions, and good thermal stability with onset decomposition temperatures greater than 100 °C.

doi: 10.1038/nature23662

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Island biogeography of marine organisms p.82

On marine islands, most species are good dispersers and most niches are filled by immigration with little adaptive radiation; speciation increases over time, associated with the arrival of weak dispersers that randomly establish isolated populations.

doi: 10.1038/nature23680

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A right-handed signalling pathway drives heart looping in vertebrates p.86

Two parallel signalling pathways, driven by Nodal and BMP, respectively integrate left- and right-handed information that drives heart looping and morphogenesis, and are conserved between zebrafish, chicken and mouse.

doi: 10.1038/nature23454

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植物科学:GLUTAMATE RECEPTOR-LIKEチャネルはコケ類における走化性と生殖に必須である

GLUTAMATE RECEPTOR-LIKE channels are essential for chemotaxis and reproduction in mosses p.91

Mutations in genes that encode GLUTAMTATE RECEPTOR-LIKE (GLR) channels in the moss Physcomitrella patens result in failure of motile sperm to target the female reproductive organs and of zygotes to develop properly.

doi: 10.1038/nature23478

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Orthotopic patient-derived xenografts of paediatric solid tumours p.96

A protocol producing orthotopic patient-derived xenografts at diagnosis, recurrence, and autopsy demonstrates proof of principle for using these tumours for basic and translational research on paediatric solid tumours.

doi: 10.1038/nature23647

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CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity p.101

CMTM6 maintains PD-L1 at the plasma membrane by inhibiting its lysosome-mediated degradation and promoting its recycling.

doi: 10.1038/nature23643

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Identification of CMTM6 and CMTM4 as PD-L1 protein regulators p.106

CMTM6 and CMTM4 bind to and stabilize the inhibitory receptor PD-L1 and regulate PD-L1 levels at the surface of human tumour and immune cells.

doi: 10.1038/nature23669

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Discovery of stimulation-responsive immune enhancers with CRISPR activation p.111

The authors use tiled CRISPR activation for functional enhancer discovery across two autoimmunity risk loci, CD69 and IL2RA, and identify elements with features of stimulus-responsive enhancers, including an IL2RA enhancer that harbours a fine-mapped autoimmunity risk variant.

doi: 10.1038/nature23875

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