Pillars of reform p.535

The Chinese government’s planned overhaul of its core research-funding system is vital if the country is to achieve its potential on the global scientific stage.

doi: 10.1038/514535a

Full Text


Call to action p.535

Time to ramp up science’s contribution to controlling the Ebola outbreak.

doi: 10.1038/514535b

Full Text

Nature およびNature 関連誌では、掲載論文中に、コンピューターコードをできるだけ公開するよう求めていく。

Code share p.536

Papers in Nature journals should make computer code accessible where possible.

doi: 10.1038/514536a

Full Text



Icelandic volcano stuns scientists p.543

Sulphur-rich eruption defies preparations for an ashy blast.

doi: 10.1038/514543a

Full Text


‘Forgotten’ NIH smallpox virus languishes on death row p.544

World Health Organization lacks resources to witness destruction of stocks.

doi: 10.1038/514544a

Full Text


Coastal havoc boosts jellies p.545

Five-year Chinese study suggests that human activity made gelatinous outbreaks worse.

doi: 10.1038/514545a

Full Text


Pet dogs set to test anti-ageing drug p.546

Trials would study extension of lifespan in domestic setting.

doi: 10.1038/514546a

Full Text


China opens translational medicine centre in Shanghai p.547

First of five linked institutes aims to capitalize on basic-research investments.

doi: 10.1038/514547a

Full Text


Geneticists tap human knockouts p.548

Sequenced genomes reveal mutations that disable single genes and can point to new drugs.

doi: 10.1038/514548a

Full Text

News Features


The top 100 papers p.550


doi: 10.1038/514550a

Full Text


The Ebola questions p.554


doi: 10.1038/514554a

Full Text

News & Views


Evolutionary developmental biology: Ghost locus appears p.570


doi: 10.1038/514570a

Full Text


Astrophysics: Secret ingredient exposed p.571


doi: 10.1038/nature13932

Full Text


Structural biology: Enzyme–chromatin complex visualized p.572


doi: 10.1038/514572a

Full Text


Materials science: Radicals promote magnetic gel assembly p.574


doi: 10.1038/514574a

Full Text


Cardiac biology: Cell plasticity helps hearts to repair p.575


doi: 10.1038/nature13928

Full Text


Immunology: Starve a fever, feed the microbiota p.576


doi: 10.1038/nature13756

Full Text



Three new Jurassic euharamiyidan species reinforce early divergence of mammals p.579

Three new euharamiyidan species from the Jurassic period of China are described, cementing the alliance with multituberculates and showing that the initial divergence between groups of extant mammals—monotremes on the one side, marsupials and placentals on the other—goes back to the Triassic period.

doi: 10.1038/nature13718

日本語要約 | Full Text | PDF


Mesenchymal–endothelial transition contributes to cardiac neovascularization p.585

This study shows that cardiac injury induces cardiac fibroblasts to undergo mesenchymal–endothelial transition and acquire an endothelial-cell like fate, a process mediated, in part, by a p53-dependent mechanism — use of a small molecule activator of p53 increases mesenchymal–endothelial transition, leading to reduced scarring and better preservation of heart function.

doi: 10.1038/nature13839

日本語要約 | Full Text | PDF


Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome p.591

The crystal structure of the PRC1 ubiquitylation module bound to its nucleosome core substrate is determined, revealing how a histone-modifying enzyme achieves substrate specificity by recognizing nucleosome surfaces distinct from the site of catalysis, and uncovering a unique role for the ubiquitin E2 enzyme in substrate recognition.

doi: 10.1038/nature13890

日本語要約 | Full Text | PDF



Spatially resolved magnetic field structure in the disk of a T Tauri star p.597

Measurements of polarized 1.25-mm continuum emission from the accretion disk of the T Tauri star HL Tau show that the magnetic field inside the disk cannot be dominated by a vertical component, and that a purely toroidal field also does not fit the data; this suggests that the role of the magnetic field in the accretion of a T Tauri star is more complex than the current theoretical understanding.

doi: 10.1038/nature13850

日本語要約 | Full Text | PDF

宇宙:若い低質量多重星系GG Tau Aにおける惑星形成の可能性

Possible planet formation in the young, low-mass, multiple stellar system GG Tau A p.600

Investigation of the triple stellar system GG Tau A reveals gas fragments within the central cavity between the Keplerian outer ring orbiting the entire system and the stars themselves; gas flow from this outer ring appears capable of sustaining the inner disk surrounding component star GG Tau Aa beyond the accretion lifetime, leaving time for planet formation to occur.

doi: 10.1038/nature13822

日本語要約 | Full Text | PDF


Quantum tomography of an electron p.603

Quantum tomography of individual electrons, which in principle yields complete knowledge of their quantum states, is demonstrated by initially preparing them in a well-controlled quantum state called a leviton.

doi: 10.1038/nature13821

日本語要約 | Full Text | PDF


Room-temperature magnetic order on zigzag edges of narrow graphene nanoribbons p.608

In graphene nanoribbons of ‘zigzag’ edge orientation, the edges host unpaired electron spins that couple to generate long-range magnetic order (switching from antiferromagnetic to ferromagnetic inter-edge configuration as the ribbon width increases) under ambient conditions, enhancing the prospects for graphene-based spintronic devices.

doi: 10.1038/nature13831

日本語要約 | Full Text | PDF


Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes p.612

Short carbon nanotubes spontaneously insert into lipid bilayers and live cell membranes to form channels with useful and tunable transport properties that make them a promising biomimetic nanopore platform for developing cell interfaces, studying nanofluidic transport in biological channels, and creating stochastic sensors.

doi: 10.1038/nature13817

日本語要約 | Full Text | PDF


Centennial-scale changes in the global carbon cycle during the last deglaciation p.616

Carbon dioxide and methane records from a West Antarctic ice core show that although gradual variations in the concentration of atmospheric carbon dioxide during the last glacial termination are linked to changes in Antarctic temperature, the concentration underwent three abrupt, centennial-scale changes related to sudden climate changes in the Northern Hemisphere.

doi: 10.1038/nature13799

日本語要約 | Full Text | PDF


Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes p.620

A study of the genomes of calcisponges shows that they contain at least one ParaHox gene, adding weight to the ‘ghost locus’ hypothesis that Hox and ParaHox genes were present in the earliest animal ancestor, but subsequently lost in some sponge lineages.

doi: 10.1038/nature13881

日本語要約 | Full Text | PDF


Non-equivalent contributions of maternal and paternal genomes to early plant embryogenesis p.624

A functional assessment of paternal gene activation in Arabidopsis confirms that paternal genome activation does not occur in one early discrete step, shows that maternal and paternal genomes do not make equivalent contributions to early plant embryogenesis, and uncovers an unexpectedly large effect of hybrid genetic background on paternal gene activity.

doi: 10.1038/nature13620

日本語要約 | Full Text | PDF


Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function p.628

KRAS mutations are a driver event of pancreatic ductal adenocarcinoma; here, a subpopulation of dormant tumour cells, relying on oxidative phosphorylation for survival, is shown to be responsible for tumour relapse after treatment targeting the KRAS pathway.

doi: 10.1038/nature13611

日本語要約 | Full Text | PDF


Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting p.633

The Staphylococcus epidermis CRISPR-Cas system can prevent lytic infection but tolerate lysogenization by temperate phage through a transcription-dependent DNA targeting mechanism.

doi: 10.1038/nature13637

日本語要約 | Full Text | PDF


Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness p.638

Systemic exposure to Toll-like receptor (TLR) ligands during sickness is shown to induce fucosylation of the small intestine in mice; some of the fucose is shed into the intestinal lumen, where it provides nourishment for the microbiota.

doi: 10.1038/nature13823

日本語要約 | Full Text | PDF


Enhanced neonatal Fc receptor function improves protection against primate SHIV infection p.642

A mutation in VRC01, a broadly neutralizing, HIV-1-specific antibody, confers enhanced binding to the neonatal Fc receptor, increasing the antibody half-life in the serum and localization in mucosal tissues, where it provides superior protection against rectal simian HIV-1 infection in macaques.

doi: 10.1038/nature13612

日本語要約 | Full Text | PDF


Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C p.646

Simultaneous disruption of two different protein–protein interactions within the (APC/C–Cdc20)–substrate complex can synergistically inhibit APC/C-dependent proteolysis and mitotic exit.

doi: 10.1038/nature13660

日本語要約 | Full Text | PDF


Transcriptional interference by antisense RNA is required for circadian clock function p.650

The transcriptions of frq sense and antisense RNAs are mutually inhibitory and form a double negative feedback loop required for robust and sustained circadian rhythmicity: antisense transcription inhibits sense expression by causing chromatin modifications and premature transcription termination.

doi: 10.1038/nature13671

日本語要約 | Full Text | PDF

「Journal home」に戻る