Research Highlights

Zinc for prostate cancer

doi:10.1038/nindia.2010.2 Published online 27 January 2010

Zinc has been shown to inhibit the growth of prostate cancer cells.

To find out the efficacy of zinc to stall cancer cells, researchers treated human androgen-independent prostatic carcinoma (PC-3) cells with different concentrations of zinc for 24 and 48 hours.

Zinc significantly reduced the cell viability of PC-3 cells. It also decreased the level of growth factors and other biochemicals that pave the way for the growth of cancer cells. The researchers found that zinc-treated cancer cells finally committed mass suicide.

The researchers say zinc may be used as a potential therapeutic agent for the treatment of prostate cancer.

The authors of this work are from: Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, Tamilnadu, India and Arizona Cancer Center, Tucson, AZ, USA.


References

  1. Banudevi, S. et al. Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells. Clin. Chim. Acta. 411, 172-178 (2010) | Article | PubMed |