Nature Hot Topic

Schizophrenia risk factors

Based on its symptoms, schizophrenia has been considered a discrete disease, and yet genome-wide association studies for copy number variations (CNVs) associated with the disease have revealed that some CNVs confer high relative risk of schizophrenia but also of other psychiatric disorders. But CNVs can affect several genes. Now, a genome-wide association of single nucleotide polymorphisms (SNPs) using data from several large genome-wide scans reveals significant associations to individual loci that implicate immunity, brain development, memory and cognition in predisposition to schizophrenia.

Nature Volume 460 Issue 7256

Top Ten Highlights

Sign up for Nature Research e-alerts to get the lastest research in your inbox every week.

More Hot Topics

PrivacyMark System