Research highlight

Variants associated with bone mineral density

Nature Genetics

October 5, 2009

Thirteen new genetic loci are associated with bone mineral density, according to a new study published online in this week's Nature Genetics.

Bone mineral density is an important clinical indicator for osteoporosis, a disease in which bone mass and bone strength are reduced and risk of bone fracture is increased. Millions of people are affected around the world, though women are more likely to develop osteoporosis than men.

Fernando Rivadeneira and colleagues identify 13 new genetic loci that are associated with bone mineral density. Many of the loci are located within or close to genes involved in bone metabolism.

doi: 10.1038/ng.446

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