Research highlight
Variant associated with bipolar disorder
Nature Genetics
September 19, 2011
A genetic variant associated with bipolar disorder is reported this week in Nature Genetics. Bipolar disorder is a severe psychiatric disorder affecting more than 1% of the population.
Pamela Sklar and colleagues from The Psychiatric GWAS Consortium Bipolar Disorder Working Group report an association study of bipolar disorder from 16,731 individuals and a replication sample of 46,918 individuals. They identify a genetic variant in the ODZ4 gene that is associated with bipolar disorder. The authors suggest a pathway comprised of subunits of calcium channels as influencing risk of bipolar disorder.
doi: 10.1038/ng.943
Research highlights
-
Oct 20
Cell biology: Viral glycoproteins may aid spread of protein aggregates associated with neurodegenerative diseasesNature Communications
-
Oct 19
Physiology: Fasting may mediate the beneficial effects of calorie restriction in miceNature Metabolism
-
Oct 12
Biomedical engineering: Exoskeleton improves walking in patients with above-knee amputationNature Medicine
-
Oct 12
Archaeology: Earliest known human use of tobacco revealedNature Human Behaviour
-
Oct 12
Sociology: Older adults worldwide exhibit increased, but more nationally focused, prosocial behaviorNature Aging
-
Oct 7
Neuroscience: Mapping the mammalian motor cortexNature
