《自然》 目录

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Quiet moments in time p.292

'Squeezed' light exhibits smaller quantum fluctuations than no light at all. Localized squeezed regions have now been produced along an infrared light wave and probed with unprecedented time resolution. See Letter p.376

Marco Bellini

doi: 10.1038/541292a

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Messenger RNAs marked for longer life p.293

A molecular modification called m6Am has been found to regulate the stability of messenger RNAs in mammalian cells. The mechanism casts fresh light on how reversibly modified RNA bases control the fate of mRNA. See Article p.371

David E. Weinberg & John D. Gross

doi: 10.1038/nature21109

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Shoppers like what they know p.294

Faced with ever-changing products, consumers can benefit from trying new items. But data collected over almost five years show that, the longer shoppers have been buying a favourite product, the more likely they are to stick with it.

Peter M. Todd

doi: 10.1038/nature21114

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Algorithm for architectural origami p.296

An algorithm has been developed allowing the rational design of origami-inspired materials that can be rearranged to change their properties. This might open the way to strategies for making reconfigurable robots. See Article p.347

Jamie Paik

doi: 10.1038/541296a

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Mind the gaps in cellular evolution p.297

Eukaryotic cells, with complex features such as membrane-bound nuclei, evolved from prokaryotic cells that lack these components. A newly identified prokaryotic group reveals intermediate steps in eukaryotic-cell evolution. See Article p.353

James O. McInerney & Mary J. O'Connell

doi: 10.1038/nature21113

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Ins and outs of picornaviruses p.299

Competition between the phospholipase enzyme PLA2G16 and the protein galectin-8 determines whether the RNA-based genomes of picornaviruses can be effectively delivered into host cells. See Letter p.412

Kevin L. McKnight & Stanley M. Lemon

doi: 10.1038/nature21116

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Articles

Genomic hallmarks of localized, non-indolent prostate cancer p.359

Michael Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, Lawrence E. Heisler, Julie Livingstone, Vincent Huang, Yu-Jia Shiah, Fouad Yousif, Xihui Lin, Andre P. Masella + et al.

doi: 10.1038/nature20788

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Reversible methylation of m6Am in the 5′ cap controls mRNA stability p.371

Fat mass and obesity-associated protein (FTO) preferentially demethylates m6Am, a modified adenosine that, when present at the 5′ end of certain mRNAs, positively influences mRNA stability by preventing DCP2-mediated decapping.

Jan Mauer, Xiaobing Luo, Alexandre Blanjoie, Xinfu Jiao, Anya V. Grozhik, Deepak P. Patil, Bastian Linder, Brian F. Pickering, Jean-Jacques Vasseur, Qiuying Chen + et al.

doi: 10.1038/nature21022

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Letters

Evolution of the global phosphorus cycle p.386

Christopher T. Reinhard, Noah J. Planavsky, Benjamin C. Gill, Kazumi Ozaki, Leslie J. Robbins, Timothy W. Lyons, Woodward W. Fischer, Chunjiang Wang, Devon B. Cole & Kurt O. Konhauser

doi: 10.1038/nature20772

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