《自然》 目录

Editorials

News

US science agencies face deep cuts in Trump budget p.471

The Environmental Protection Agency and the National Institutes of Health are big losers — but planetary science at NASA stands to gain.

Sara Reardon, Jeff Tollefson, Alexandra Witze & Erin Ross

doi: 10.1038/nature.2017.21652

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News Features

News & Views

Dividing the dinosaurs p.494

The standard dinosaur evolutionary tree has two key branches: the 'bird-hipped' Ornithischia and the 'reptile-hipped' Saurischia. A revised tree challenges many ideas about the relationships between dinosaur groups. See Article p.501

Kevin Padian

doi: 10.1038/543494a

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Bacterial transmission tactics p.495

Genome sequencing of Mycobacterium abscessus strains that infect the lungs suggests a possible shift in the bacterium's mode of infection from environmental acquisition to human transmission. This finding has clinical implications.

Michael Strong & Rebecca M. Davidson

doi: 10.1038/543495a

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Vibrations mapped by an electron beam p.497

The vibrational excitations of nanostructures have been mapped using state-of-the-art electron microscopy. The results improve our understanding of these excitations, which will aid the design of nanostructures. See Letter p.529

Christian Colliex

doi: 10.1038/543497a

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A helping habitat for bumblebees p.498

A study showing the effects of land-use quality on the productivity of bumblebee colonies highlights the importance of resource availability across space and time in promoting survival over generations. See Letter p.547

Jeffrey D. Lozier

doi: 10.1038/nature21897

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Articles

A new hypothesis of dinosaur relationships and early dinosaur evolution p.501

Analysis of a wide range of dinosaurs and dinosauromorphs recovers a sister-taxon relationship between Ornithischia and Theropoda, calling for the redefinition of all the major clades within Dinosauria and the revival of the clade Ornithoscelida.

Matthew G. Baron, David B. Norman & Paul M. Barrett

doi: 10.1038/nature21700

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Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1 p.507

Increasing expression of the autism-associated gene Ube3a, either alone or in combination with seizures, not only impairs sociability in mice but also reduces expression of the synaptic organizer Cbln1 in the ventral tegmental area, thus weakening glutamatergic transmission.

Vaishnav Krishnan, David C. Stoppel, Yi Nong, Mark A. Johnson, Monica J. S. Nadler, Ekim Ozkaynak, Brian L. Teng, Ikue Nagakura, Fahim Mohammad, Michael A. Silva + et al.

doi: 10.1038/nature21678

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Root microbiota drive direct integration of phosphate stress and immunity p.513

In Arabidopsis thaliana, a genetic network that controls the phosphate stress response also influences the structure of the root microbiome community, even under non-stress phosphate conditions.

Gabriel Castrillo, Paulo José Pereira Lima Teixeira, Sur Herrera Paredes, Theresa F. Law, Laura de Lorenzo, Meghan E. Feltcher, Omri M. Finkel, Natalie W. Breakfield, Piotr Mieczkowski, Corbin D. Jones + et al.

doi: 10.1038/nature21417

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Complex multi-enhancer contacts captured by genome architecture mapping p.519

A technique called genome architecture mapping (GAM) involves sequencing DNA from a large number of thin nuclear cryosections to develop a map of genome organization without the limitations of existing 3C-based methods.

Robert A. Beagrie, Antonio Scialdone, Markus Schueler, Dorothee C. A. Kraemer, Mita Chotalia, Sheila Q. Xie, Mariano Barbieri, Inês de Santiago, Liron-Mark Lavitas, Miguel R. Branco + et al.

doi: 10.1038/nature21411

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Letters

Simultaneous tracking of spin angle and amplitude beyond classical limits p.525

Simultaneous precise measurement of the non-commuting observables spin angle and spin amplitude is achieved by directing the error due to quantum measurement back-action into an unmeasured spin component.

Giorgio Colangelo, Ferran Martin Ciurana, Lorena C. Bianchet, Robert J. Sewell & Morgan W. Mitchell

doi: 10.1038/nature21434

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Bumblebee family lineage survival is enhanced in high-quality landscapes p.547

Analysis of three wild-caught bumblebee species shows that family lineage survival and persistence is significantly increased between successive colony cycle stages with the proportion of high-value foraging habitat near the natal colony.

Claire Carvell, Andrew F. G. Bourke, Stephanie Dreier, Stephen N. Freeman, Sarah Hulmes, William C. Jordan, John W. Redhead, Seirian Sumner, Jinliang Wang & Matthew S. Heard

doi: 10.1038/nature21709

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Early antibody therapy can induce long-lasting immunity to SHIV p.559

Early administration of broadly neutralizing antibodies in a macaque SHIV infection model is associated with very low levels of persistent viraemia, which leads to the establishment of T-cell immunity and resultant long-term infection control.

Yoshiaki Nishimura, Rajeev Gautam, Tae-Wook Chun, Reza Sadjadpour, Kathryn E. Foulds, Masashi Shingai, Florian Klein, Anna Gazumyan, Jovana Golijanin, Mitzi Donaldson + et al.

doi: 10.1038/nature21435

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CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses p.564

CD32a expression is induced on the surface of HIV-1-infected quiescent CD4 T cells, and could thus be used as a biomarker to facilitate future study of how the virus persists in cellular reservoirs in infected hosts.

Benjamin Descours, Gaël Petitjean, José-Luis López-Zaragoza, Timothée Bruel, Raoul Raffel, Christina Psomas, Jacques Reynes, Christine Lacabaratz, Yves Levy, Olivier Schwartz + et al.

doi: 10.1038/nature21710

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DND1 maintains germline stem cells via recruitment of the CCR4–NOT complex to target mRNAs p.568

The vertebrate-conserved and germline-specific RNA-binding protein DND1 recruits the CCR4–NOT deadenylase complex to destabilize its mRNA targets and is required for the maintenance of germline stem cells.

Masashi Yamaji, Miki Jishage, Cindy Meyer, Hemant Suryawanshi, Evan Der, Misaki Yamaji, Aitor Garzia, Pavel Morozov, Sudhir Manickavel, Hannah L. McFarland + et al.

doi: 10.1038/nature21690

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RNA m6A methylation regulates the ultraviolet-induced DNA damage response p.573

Methylation at the 6 position of adenosine (m6A) in RNA is rapidly and transiently induced at DNA damage sites in response to ultraviolet irradiation.

Yang Xiang, Benoit Laurent, Chih-Hung Hsu, Sigrid Nachtergaele, Zhike Lu, Wanqiang Sheng, Chuanyun Xu, Hao Chen, Jian Ouyang, Siqing Wang + et al.

doi: 10.1038/nature21671

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