: Microbiology Articles
Review: Bacterial nucleoid-associated proteins, nucleoid structure and gene expressionEmerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs) and transcription contribute in combination to the dynamic nature of nucleoid structure. NAPs and other DNA-binding proteins that display gene-silencing and anti-silencing activities are emerging as key antagonistic regulators of nucleoid structure. Furthermore, it Nature Reviews Microbiology, vol. 8 #3, pp185-195 |
Review: The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genesIn several host-adapted pathogens, phase variation has been found to occur in genes that encode methyltransferases associated with type III restriction?modification systems. It was recently shown that in the human pathogens Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis phase variation of a Nature Reviews Microbiology, vol. 8 #3, pp196-206 |
Review: Viral shape-shifting: norovirus evasion of the human immune systemNoroviruses are the most common cause of food-borne gastroenteritis worldwide, and explosive outbreaks frequently occur in community settings, where the virus can immobilize large numbers of infected individuals for 24?48 hours, making the development of effective vaccines and antiviral therapies a priority. However, several challenges Nature Reviews Microbiology, vol. 8 #3, pp231-241 |
Research Highlight: Archaea: Singled out from the crowdA recent discovery shows that Archaea have a protein conjugation system similar to eukaryotic ubiquitylation. Nature Reviews Microbiology, vol. 8 #3, pp160-160 |
Research Highlight: Symbiosis: Breaking the rhizobial barrierExperimental evolution of symbiotic behaviour in the root-infecting pathogen Ralstonia solanacearum. Nature Reviews Microbiology, vol. 8 #3, pp157-157 |
Review: A complex journey: transmission of microbial symbiontsThe perpetuation of symbioses through host generations relies on symbiont transmission. Horizontally transmitted symbionts are taken up from the environment anew by each host generation, and vertically transmitted symbionts are most often transferred through the female germ line. Mixed modes also exist. In this Review Nature Reviews Microbiology, vol. 8 #3, pp218-230 |
Review: Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogensHow can probiotic bacteria transduce their health benefits to the host? Bacterial cell surface macromolecules are key factors in this beneficial microorganism?host crosstalk, as they can interact with host pattern recognition receptors (PRRs) of the gastrointestinal mucosa. In this Review, we highlight the documented signalling Nature Reviews Microbiology, vol. 8 #3, pp171-184 |
Review: The population genetics of commensal Escherichia coliThe primary habitat of Escherichia coli is the vertebrate gut, where it is the predominant aerobic organism, living in symbiosis with its host. Despite the occurrence of recombination events, the population structure is predominantly clonal, allowing the delineation of major phylogenetic groups. The genetic Nature Reviews Microbiology, vol. 8 #3, pp207-217 |
Research Highlight: Parasitology: Epigenetic regulation of VSG expressionTwo papers in Eukaryotic Cell show that nucleosomes are depleted at active variant surface glycoprotein (VSG) gene expression sites. Nature Reviews Microbiology, vol. 8 #3, pp160-160 |
Research Highlight: Viral infection: miRNAs help KSHV lay lowMicroRNAs regulate KSHV latency through different mechanisms. Nature Reviews Microbiology, vol. 8 #3, pp158-159 |
Research Highlight: In BriefVirology Nature Reviews Microbiology, vol. 8 #3, pp158-158 |
Research Highlight: In BriefBacterial pathogenicity Nature Reviews Microbiology, vol. 8 #3, pp159-159 |
Research Highlight: Industrial microbiology: Fuelling the renewable revolutionEscherichia coli can be rationally engineered to produce structurally tailored fatty acids and their derivatives from simple sugars and plant-derived biomass. Nature Reviews Microbiology, vol. 8 #3, pp158-159 |
