Immunology Articles

Editorial: Educating the public

California has one of the most prestigious public university systems. However, budget woes and lack of clear strategic planning may undermine its continued success.

Nature Immunology, vol. 11 #3, pp181-181

News and Views: Vanilloid flavor for a good appetite?

Members of the transient receptor potential vanilloid ion-channel family are expressed in a wide variety of cells and function as sensors of mechanical stress. The second such family member, TVRP2, is now also linked to phagocytosis in macrophages.

Nature Immunology, vol. 11 #3, pp187-189

News and Views: CD8+ thymocyte differentiation: T cell two-step

A new study demonstrates that commitment to the CD8 lineage in the thymus requires sequential T cell antigen receptor (TCR) and interleukin 7 (IL-7) signaling. The TCR signal first induces IL-7 responsiveness, then recognition of IL-7 induces the nuclear factor Runx3, which specifies the CD8 lineage.

Nature Immunology, vol. 11 #3, pp189-190

News and Views: Voltage control for B cell activation

Transient formation of reactive oxygen species (ROS) accompanies B cell signaling and activation. Now the voltage-gated proton channel HVCN1 has been linked to ROS formation and B cell activation.

Nature Immunology, vol. 11 #3, pp191-192

News and Views: Controlling stem cell fate one substrate at a time

Hematopoietic stem cell self-renewal is tightly regulated. Regulation of the stability of c-Myc protein contributes to this control of hematopoietic stem cell quiescence and repopulation.

Nature Immunology, vol. 11 #3, pp193-194



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