Immunology Articles

Editorial: On the move

Leukocytes express an array of chemoattractant and adhesion receptors that govern their migration, behavior and survival.

Nature Immunology, vol. 9 #9, pp947-947

News and Views: The making of NKT cells

Natural killer T cells acquire their unique phenotype and characteristics during development in the thymus. Evidence suggests that the transcription factor PLZF has a unique function in the development of these cells and their acquisition of 'innate-like' characteristics.

Nature Immunology, vol. 9 #9, pp1009-1011

News and Views: The CD200-CD200R axis in local control of lung inflammation

Excessive lung inflammation in response to infection or allergens can lead to tissue damage and potentially loss of organ function. The CD200-CD200R interaction acts to limit such destructive immune responses in the lung.

Nature Immunology, vol. 9 #9, pp1011-1013

News and Views: A birthday gift for TRADD

Definitive new data solidify and clarify the function of the adaptor TRADD in tumor necrosis factor receptor 1 signaling and show that in some situations, TRADD is also required for the transmission of Toll-like receptor signals.

Nature Immunology, vol. 9 #9, pp1015-1016

News and Views: Regulation of NKG2D ligands: a purposeful but delicate affair

New findings show that cellular microRNAs 'calibrate' the baseline expression of mRNAs encoding stress-inducible ligands of the activating NKG2D receptor. This regulation serves to protect innocent cells but may be exploited by tumors and viruses to thwart immune attack.

Nature Immunology, vol. 9 #9, pp1013-1015



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