p.7

On the tenth anniversary of the discovery of the Higgs boson, it’s worth emphasizing that there’s a lot more to particle physics than particle hunting.

doi: 10.1038/d41586-022-01819-4

p.8

European nations led the world in promoting strong climate action. They risk undoing all of that work now that European energy security is at risk.

doi: 10.1038/d41586-022-01820-x

p.15

Years of studies point to the negative economic and health effects of restricting access to abortions.

doi: 10.1038/d41586-022-01775-z

p.17

African researchers have been warning about monkeypox outbreaks for years. As vaccines are deployed globally, they worry they will be left behind.

doi: 10.1038/d41586-022-01686-z

p.18

COVID-19 vaccines are due for an upgrade, scientists say, but emerging variants and fickle immune reactions mean it’s not clear what new jabs should look like.

doi: 10.1038/d41586-022-01771-3

p.20

US cases of liver inflammation among children have remained flat, but UK cases seem to have risen, leading some to suggest a coronavirus contribution.

doi: 10.1038/d41586-022-01706-y

p.21

Meteorologists are forecasting a third consecutive year of La Niña. Some researchers say similar conditions could become more common as the planet warms.

doi: 10.1038/d41586-022-01668-1

p.22

doi: 10.1038/d41586-022-01827-4

p.33

The deadly spread of cancer occurs predominantly during sleep, as revealed by an analysis of migrating human tumour cells in the bloodstream. What are the implications of this finding for the treatment of cancer?

doi: 10.1038/d41586-022-01639-6

p.34

A mechanism resembling a crankshaft switches the electric polarization of a material in response to changes in an applied magnetic field. The resulting four-state switch is linked to the material’s intriguing topology.

doi: 10.1038/d41586-022-01786-w

p.36

The sensation of touch-evoked itch is common in people who have chronic itch conditions. Evidence in mice now suggests that the mechanoreceptor protein Piezo1 underlies this sensation.

doi: 10.1038/d41586-022-01571-9

p.37

Enzymes use molecular clusters containing iron and sulfur atoms to bind and ‘fix’ nitrogen gas into a bioavailable form. A synthetic cluster that binds and reduces nitrogen molecules casts light on the mechanism of fixation.

doi: 10.1038/d41586-022-01787-9

p.39

The trigeminal nerve has a key role in migraine. An atlas of cell types and gene-expression profiles for cells in this nerve in mice and humans promises to improve our understanding of head pain.

doi: 10.1038/d41586-022-01479-4

p.41

doi: 10.1038/s41586-022-04899-4

p.48

doi: 10.1038/s41586-022-04813-y

p.52

doi: 10.1038/s41586-022-04893-w

p.60

doi: 10.1038/s41586-022-04892-x

p.69

doi: 10.1038/s41586-022-04764-4

p.74

doi: 10.1038/s41586-022-04794-y

p.81

doi: 10.1038/s41586-022-04851-6

p.86

doi: 10.1038/s41586-022-04848-1

p.91

doi: 10.1038/s41586-022-04861-4

p.97

doi: 10.1038/s41586-022-04576-6

p.104

doi: 10.1038/s41586-022-04860-5

p.111

doi: 10.1038/s41586-022-04862-3

p.119

doi: 10.1038/s41586-022-04856-1

p.128

doi: 10.1038/s41586-022-04778-y

p.135

doi: 10.1038/s41586-022-04849-0

p.142

doi: 10.1038/s41586-022-04866-z

p.149

doi: 10.1038/s41586-022-04839-2

p.156

doi: 10.1038/s41586-022-04875-y

p.163

doi: 10.1038/s41586-022-04888-7

p.169

doi: 10.1038/s41586-022-04842-7

p.176

doi: 10.1038/s41586-022-04877-w

p.185

doi: 10.1038/s41586-022-04858-z

p.191

doi: 10.1038/s41586-022-04859-y