Le Pen election win would be disastrous for research, France and Europe p.401

Marine Le Pen is promising to repeal unpopular changes to research institutions. But the wider impact of her presidency would be catastrophic.

doi: 10.1038/d41586-022-01043-0

How Shanghai’s scientists are coping amid harsh COVID lockdown p.409

From laps of the apartment to fears for students who desperately need data, four researchers speak about their lockdown experience.

doi: 10.1038/d41586-022-01052-z

Jury finds University of Kansas chemical engineer guilty of hiding ties to China p.410

After a two-week trial, Feng ‘Franklin’ Tao was convicted on four of eight charges — but a judge is reviewing the case.

doi: 10.1038/d41586-022-01022-5

African clinical trial denied access to key COVID drug Paxlovid p.412

Supply shortages and limits on research leave low- and middle-income countries struggling to access Pfizer’s COVID-19 antiviral.

doi: 10.1038/d41586-022-00919-5

IPCC’s starkest message yet: extreme steps needed to avert climate disaster p.413

Radical emissions cuts combined with some atmospheric carbon removal are the only hope to limit global warming to 1.5 °C, scientists warn.

doi: 10.1038/d41586-022-00951-5

Ancient smells reveal secrets of Egyptian tomb p.414

Jars contained fish, fruit and beeswax balm to sustain the tomb’s residents in the afterlife.

doi: 10.1038/d41586-022-00903-z

China is hatching a plan to find Earth 2.0 p.415

A satellite will scour the Milky Way for exoplanets orbiting stars just like the Sun.

doi: 10.1038/d41586-022-01025-2

The brain-reading devices helping paralysed people to move, talk and touch p.416

doi: 10.1038/d41586-022-01047-w

Insights from orangutans into the evolution of tool use p.427

Gaining the ability to make stone tools was a useful development for early human ancestors in the hominin branch of the evolutionary tree. Could studying orangutans provide clues to how this behaviour arose?

doi: 10.1038/d41586-022-00872-3

Versatile neutral atoms take on quantum circuits p.429

Neutral atoms are fast becoming prime candidates for use in quantum computers. Two studies involving multiple quantum bits show how this platform enables creative solutions for building quantum circuits.

doi: 10.1038/d41586-022-01029-y

A lengthy look at climate and its role in hominin evolution p.430

Climate effects on ecosystems shaped the evolution of our hominin relatives in the human family tree. A modelling study examines these habitat changes and the various ways in which they influenced hominin species.

doi: 10.1038/d41586-022-00975-x

Marine heatwaves are reliably forecast by climate models p.432

Climate models can provide accurate seasonal forecasts of unusually warm ocean temperatures, enabling the models’ predictions to guide decisions made by stakeholders in the marine industries and conservation.

doi: 10.1038/d41586-022-01028-z

Genetic origins of schizophrenia find common ground p.433

Two differing approaches that are used to study common and rare genetic causes of schizophrenia reveal convergent clues about the biology underlying this complex disorder.

doi: 10.1038/d41586-022-00773-5

Mutational clocks tick differently across species p.435

Throughout life, cells accrue mutations. It now emerges that longer-lived animals acquire mutations at a slower rate than do short-lived species, potentially explaining why cancer risk does not increase with lifespan.

doi: 10.1038/d41586-022-00976-w

The Human Pangenome Project: a global resource to map genomic diversity p.437

doi: 10.1038/s41586-022-04601-8

Localized thermonuclear bursts from accreting magnetic white dwarfs p.447

doi: 10.1038/s41586-022-04495-6

A quantum processor based on coherent transport of entangled atom arrays p.451

doi: 10.1038/s41586-022-04592-6

Multi-qubit entanglement and algorithms on a neutral-atom quantum computer p.457

doi: 10.1038/s41586-022-04603-6

Quantum state preparation and tomography of entangled mechanical resonators p.463

doi: 10.1038/s41586-022-04500-y

Light-induced ferromagnetism in moiré superlattices p.468

doi: 10.1038/s41586-022-04472-z

Triplet fusion upconversion nanocapsules for volumetric 3D printing p.474

doi: 10.1038/s41586-022-04485-8

Revitalizing interface in protonic ceramic cells by acid etch p.479

doi: 10.1038/s41586-022-04457-y

Global seasonal forecasts of marine heatwaves p.486

doi: 10.1038/s41586-022-04573-9

A plume origin for hydrous melt at the lithosphere–asthenosphere boundary p.491

doi: 10.1038/s41586-022-04483-w

Climate effects on archaic human habitats and species successions p.495

doi: 10.1038/s41586-022-04600-9

Mapping genomic loci implicates genes and synaptic biology in schizophrenia p.502

doi: 10.1038/s41586-022-04434-5

Rare coding variants in ten genes confer substantial risk for schizophrenia p.509

doi: 10.1038/s41586-022-04556-w

Somatic mutation rates scale with lifespan across mammals p.517

doi: 10.1038/s41586-022-04618-z

Brain charts for the human lifespan p.525

doi: 10.1038/s41586-022-04554-y

Mapping human haematopoietic stem cells from haemogenic endothelium to birth p.534

doi: 10.1038/s41586-022-04571-x

Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile p.541

doi: 10.1038/s41586-022-04545-z

Molecular basis of receptor binding and antibody neutralization of Omicron p.546

doi: 10.1038/s41586-022-04581-9

Antibody evasion properties of SARS-CoV-2 Omicron sublineages p.553

doi: 10.1038/s41586-022-04594-4

Activation of STING by targeting a pocket in the transmembrane domain p.557

doi: 10.1038/s41586-022-04559-7

CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours p.563

doi: 10.1038/s41586-022-04585-5

Nonlinear control of transcription through enhancer–promoter interactions p.571

doi: 10.1038/s41586-022-04570-y

Structure of active human telomerase with telomere shelterin protein TPP1 p.578

doi: 10.1038/s41586-022-04582-8