COVID is here to stay: countries must decide how to adapt p.165

The Omicron variant has laid bare the need to live with a disease that throws up an ever-changing set of challenges.

doi: 10.1038/d41586-022-00057-y

Research evaluation needs to change with the times p.166

The focus on a narrow set of metrics leads to a lack of diversity in the types of leader and institution that win funding.

doi: 10.1038/d41586-022-00056-z

Elizabeth Holmes verdict: researchers share lessons for science p.173

Theranos case highlights the importance of peer review for biotech entrepreneurs, scientists say.

doi: 10.1038/d41586-022-00006-9

Researchers fear growing COVID vaccine hesitancy in developing nations p.174

Scientists worry that pools of unvaccinated people could be a source of new variants, such as Omicron.

doi: 10.1038/d41586-021-03830-7

Fatal lab explosion in China highlights wider safety fears p.176

Deaths caused by university lab blasts have some scientists in China concerned about a lack of oversight and standardized safety protocols, especially in teaching labs.

doi: 10.1038/d41586-021-03589-x

Omicron’s feeble attack on the lungs could make it less dangerous p.177

Mounting evidence from animal studies suggests that Omicron does not multiply readily in lung tissue, which can be badly damaged in people infected with other variants.

doi: 10.1038/d41586-022-00007-8

Landmark Colombian bird study repeated to right colonial-era wrongs p.178

A re-run of a 100-year-old, US-led bird survey will inform future conservation efforts — but be helmed by local researchers.

doi: 10.1038/d41586-021-03527-x

The COVID generation: how is the pandemic affecting kids’ brains? p.180

doi: 10.1038/d41586-022-00027-4

The devastating mudslides that follow forest fires p.184

doi: 10.1038/d41586-022-00028-3

Extreme rainfall slows the global economy p.193

Excessive rainfall can cause catastrophic socio-economic losses to a community or nation. An analysis of changes in gross regional product identifies ways in which extreme precipitation affects global economic productivity.

doi: 10.1038/d41586-021-03783-x

Transporter-protein structures show how salt gets a sweet ride into cells p.194

Proteins spanning the membranes of cells of the intestine and kidney use sodium-ion gradients to take up glucose, enabling water absorption, too. The structures of these transporter proteins have now been observed in detail.

doi: 10.1038/d41586-021-03555-7

A microbe that uses crude oil to make methane p.196

A microorganism that dwells in an underground oil reservoir has been found to degrade various petroleum compounds and use them to produce methane through a previously unreported biochemical pathway.

doi: 10.1038/d41586-021-03729-3

A strange metal emerges from a failed superconductor p.198

The curious electrical resistance that gives strange metals their name has been seen in a failed superconductor, in which disorder interferes with the material’s ability to achieve zero resistance below a critical temperature.

doi: 10.1038/d41586-021-03831-6

Beads reveal long-distance connections in early Africa p.199

Beads made from ostrich eggshells, produced by people over the past 50,000 years, provide evidence for a long period of social connection between eastern and southern Africa, followed by isolation and then reconnection.

doi: 10.1038/d41586-021-03681-2

A WC/WO star exploding within an expanding carbon–oxygen–neon nebula p.201

doi: 10.1038/s41586-021-04155-1

Signatures of a strange metal in a bosonic system p.205

doi: 10.1038/s41586-021-04239-y

A crossbar array of magnetoresistive memory devices for in-memory computing p.211

doi: 10.1038/s41586-021-04196-6

Elastomeric electrolytes for high-energy solid-state lithium batteries p.217

doi: 10.1038/s41586-021-04209-4

The effect of rainfall changes on economic production p.223

doi: 10.1038/s41586-021-04283-8

Air pollution exposure disparities across US population and income groups p.228

doi: 10.1038/s41586-021-04190-y

Ostrich eggshell beads reveal 50,000-year-old social network in Africa p.234

doi: 10.1038/s41586-021-04227-2

Adaptive stimulus selection for consolidation in the hippocampus p.240

doi: 10.1038/s41586-021-04118-6

NLRs guard metabolism to coordinate pattern- and effector-triggered immunity p.245

doi: 10.1038/s41586-021-04219-2

Towards the biogeography of prokaryotic genes p.252

doi: 10.1038/s41586-021-04233-4

Non-syntrophic methanogenic hydrocarbon degradation by an archaeal species p.257

doi: 10.1038/s41586-021-04235-2

Cancer risk across mammals p.263

doi: 10.1038/s41586-021-04224-5

HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 p.268

doi: 10.1038/s41586-021-04261-0

Structure and mechanism of the SGLT family of glucose transporters p.274

doi: 10.1038/s41586-021-04211-w

Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter p.280

doi: 10.1038/s41586-021-04212-9