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A special issue on COVID-era research collaboration highlights the benefits to science and society of working across borders, cultures and disciplines.

doi: 10.1038/d41586-021-01581-z

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But a thriving relationship needs clearer rules around data ownership and intellectual property – and public trust in the process.

doi: 10.1038/d41586-021-01580-0

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Many scientists say there is not enough evidence that Biogen’s aducanumab is an effective therapy for the disease.

doi: 10.1038/d41586-021-01546-2

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doi: 10.1038/d41586-021-01501-1

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Mass vaccination drives in several countries are providing new data on the extent to which adult vaccination protects children — but the conclusions are mixed.

doi: 10.1038/d41586-021-01549-z

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doi: 10.1038/d41586-021-01529-3

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doi: 10.1038/d41586-021-01570-2

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doi: 10.1038/d41586-021-01584-w

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A model of the world’s rivers and streams has been developed to predict which of these watercourses flow all year round and which go dry. The analysis shows that rivers and streams that run dry are ubiquitous throughout the world.

doi: 10.1038/d41586-021-01528-4

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Digital contact tracing has the potential to limit the spread of COVID-19. A contact-tracing smartphone app that has been readily adopted by people in England and Wales has shown efficacy in reducing disease spread.

doi: 10.1038/d41586-021-01354-8

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AMPA receptors are a class of protein complexes crucial for neuronal communication. Two complementary studies converge on structures of AMPA receptors found in a brain region called the hippocampus.

doi: 10.1038/d41586-021-01380-6

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Malignant stem cells in the gut secrete factors that promote the differentiation of neighbouring stem cells, thereby aiding the replacement of normal stem cells by those with cancer-promoting mutations.

doi: 10.1038/d41586-021-01379-z

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Examination of the molecular interactions that govern the assembly of neural circuits in a brain region called the hippocampus reveals that neuronal projections are guided to their targets by both attractive and repulsive cues.

doi: 10.1038/d41586-021-01502-0

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Observations suggest that an unexpected dimming of the massive star Betelgeuse resulted from dust forming over a cold patch in the star’s southern hemisphere. This finding improves our understanding of such massive stars.

doi: 10.1038/d41586-021-01526-6

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doi: 10.1038/s41586-021-03499-y

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doi: 10.1038/s41586-021-03453-y

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doi: 10.1038/s41586-021-03546-8

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doi: 10.1038/s41586-021-03557-5

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doi: 10.1038/s41586-021-03543-x

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doi: 10.1038/s41586-021-03564-6

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doi: 10.1038/s41586-021-03551-x

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doi: 10.1038/s41586-021-03565-5

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doi: 10.1038/s41586-021-03552-w

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doi: 10.1038/s41586-021-03593-1

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doi: 10.1038/s41586-021-03606-z

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doi: 10.1038/s41586-021-03531-1

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doi: 10.1038/s41586-021-03515-1

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doi: 10.1038/s41586-021-03572-6

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doi: 10.1038/s41586-021-03525-z

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doi: 10.1038/s41586-021-03558-4

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doi: 10.1038/s41586-021-03605-0

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doi: 10.1038/s41586-021-03540-0

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doi: 10.1038/s41586-021-03613-0