Volume 591 Issue 7849



Anniversaries of the Fukushima and Chernobyl disasters highlight the challenges of relying on nuclear power to cut net carbon emissions to zero.

doi: 10.1038/d41586-021-00615-w


The idea that ecosystems have monetary value now has global support — and creates a route to protecting Earth’s endangered regions.

doi: 10.1038/d41586-021-00616-9



A Nature poll shows that a year of online research conferences has brought big benefits, but blending them with in-person meetings in future will be a challenge.

doi: 10.1038/d41586-021-00513-1


The American Physical Society’s new criteria for conference venues seem to be unique among scientific societies.

doi: 10.1038/d41586-021-00492-3


doi: 10.1038/d41586-021-00502-4


doi: 10.1038/d41586-021-00590-2


Ramped-up sequencing efforts are helping to identify mutations that might boost transmission or help a virus evade immune responses.

doi: 10.1038/d41586-021-00564-4


The contested allegations highlight how political tensions could be affecting research.

doi: 10.1038/d41586-021-00524-y

News Features


doi: 10.1038/d41586-021-00578-y

News & Views


Technological advances offer new ways to investigate the contribution that changing climate and genes have made in shaping past migrations by peregrine falcons. Can this help to predict the fate of future migrations?

doi: 10.1038/d41586-021-00510-4


Cancer can evade destruction by the immune system if aided by immunosuppressive regulatory T cells. These cells depend on a lipid-production pathway in the tumour environment, a vulnerability that might be used to target them.

doi: 10.1038/d41586-021-00421-4


Evidence of a rare neutrino-interaction process called the Glashow resonance has been observed by a detector buried deep in the Antarctic ice — opening up a way to probe neutrino formation in astrophysical sources.

doi: 10.1038/d41586-021-00486-1


DNA has been retrieved from mammoth specimens that are more than one million years old. Comparing the genomes of these animals and their descendants provides insights into the changes that occurred as one species evolved into another.

doi: 10.1038/d41586-021-00348-w


An experiment shows that Newton’s law of gravity holds even for two masses as small as about 90 milligrams. The findings take us a step nearer to measuring gravitational fields that are so weak that they could enter the quantum regime.

doi: 10.1038/d41586-021-00591-1



doi: 10.1038/s41586-021-03243-6



Identification of a metabolic checkpoint involving lipid signalling that is specific to regulatory T cells (Treg cells) in the tumour microenvironment raises the possibility of targeting this checkpoint for treatment of cancer.

doi: 10.1038/s41586-021-03235-6


A CRISPR screen in mouse embryonic stem cells shows that transcripts derived from endogenous retroviruses are destabilized by m6A RNA methylation.

doi: 10.1038/s41586-020-03135-1


Binding of METTL3 to chromatin is enriched over IAP family endogenous retroviral elements in mouse embryonic stem cells, helping to ensure the integrity of heterochromatin at these elements.

doi: 10.1038/s41586-021-03210-1


N6-methyladenosine RNA and its reader YTHDC1 serve as a bridge to silencing retrotransposons through the RNA derived from these retrotransposons in mouse ES cells.

doi: 10.1038/s41586-021-03313-9