The quantum Hall effect continues to reveal its secrets to mathematicians and physicists p.659

doi: 10.1038/d41586-020-02230-7

The Trump administration must stop sidelining the CDC p.660

The US government needs to strengthen the agency charged with preventing the spread of disease — not undermine it.

doi: 10.1038/d41586-020-02231-6

Ebola prepared these countries for coronavirus — but now even they are floundering p.667

In Liberia, Sierra Leone and Guinea, the hard-won lessons of a deadly pandemic cannot entirely compensate for poverty and weak health systems.

doi: 10.1038/d41586-020-02173-z

Coronavirus vaccines leap through safety trials — but which will work is anybody’s guess p.669

Scientists caution against comparing immune responses shown in early-stage trials, and say there might be more than one path to an effective vaccine.

doi: 10.1038/d41586-020-02174-y

Controversial cave discoveries suggest humans reached Americas much earlier than thought p.670

Archaeologists say stone artefacts point to occupation more than 30,000 years ago — but not everyone is convinced.

doi: 10.1038/d41586-020-02190-y

China’s successful launch of Mars mission seals global era in deep-space exploration p.671

Tianwen-1 is the second of three spacecraft set to take off this month for the red planet.

doi: 10.1038/d41586-020-02187-7

‘Our epidemic could exceed a million cases’ — South Africa’s top coronavirus adviser p.672

doi: 10.1038/d41586-020-02216-5

Pluto’s dark side spills its secrets — including hints of a hidden ocean p.674

doi: 10.1038/d41586-020-02082-1

Expanded ENCODE delivers invaluable genomic encyclopedia p.685

doi: 10.1038/d41586-020-02139-1

The Phoenix stellar stream rose from the ashes of an ancient star cluster p.687

doi: 10.1038/d41586-020-02046-5

An umbrella approach to test lung cancer therapies p.688

A clinical trial has tested the use of gene-sequencing results for lung cancer to match patients to targeted therapies. Some paired treatments were a good fit, but others did not succeed, for reasons that will require further exploration.

doi: 10.1038/d41586-020-02062-5

Growth-mediated sensing of long-term cold in plants p.690

The prolonged cold of winter is required for the flowering of many plants. Now the identification of a previously unknown long-term cold-sensing mechanism helps to reveal how plants are able to time their flowering correctly.

doi: 10.1038/d41586-020-02060-7

Perspectives on ENCODE p.693

doi: 10.1038/s41586-020-2449-8

Expanded encyclopaedias of DNA elements in the human and mouse genomes p.699

doi: 10.1038/s41586-020-2493-4

A large-scale binding and functional map of human RNA-binding proteins p.711

doi: 10.1038/s41586-020-2077-3

Occupancy maps of 208 chromatin-associated proteins in one human cell type p.720

doi: 10.1038/s41586-020-2023-4

Global reference mapping of human transcription factor footprints p.729

doi: 10.1038/s41586-020-2528-x

Landscape of cohesin-mediated chromatin loops in the human genome p.737

doi: 10.1038/s41586-020-2151-x

An atlas of dynamic chromatin landscapes in mouse fetal development p.744

doi: 10.1038/s41586-020-2093-3

Spatiotemporal DNA methylome dynamics of the developing mouse fetus p.752

doi: 10.1038/s41586-020-2119-x

The changing mouse embryo transcriptome at whole tissue and single-cell resolution p.760

doi: 10.1038/s41586-020-2536-x

The tidal remnant of an unusually metal-poor globular cluster p.768

doi: 10.1038/s41586-020-2483-6

Night-time measurements of astronomical seeing at Dome A in Antarctica p.771

doi: 10.1038/s41586-020-2489-0

Waveguide quantum electrodynamics with superconducting artificial giant atoms p.775

doi: 10.1038/s41586-020-2529-9

Deep strong light–matter coupling in plasmonic nanoparticle crystals p.780

doi: 10.1038/s41586-020-2508-1

Coherent many-body exciton in van der Waals antiferromagnet NiPS₃ p.785

doi: 10.1038/s41586-020-2520-5

A fabrication process for flexible single-crystal perovskite devices p.790

doi: 10.1038/s41586-020-2526-z

North Atlantic climate far more predictable than models imply p.796

doi: 10.1038/s41586-020-2525-0

Global status and conservation potential of reef sharks p.801

doi: 10.1038/s41586-020-2519-y

The National Lung Matrix Trial of personalized therapy in lung cancer p.807

doi: 10.1038/s41586-020-2481-8

Two dynamically distinct circuits drive inhibition in the sensory thalamus p.813

doi: 10.1038/s41586-020-2512-5

Distinct subnetworks of the thalamic reticular nucleus p.819

doi: 10.1038/s41586-020-2504-5

Temperature-dependent growth contributes to long-term cold sensing p.825

doi: 10.1038/s41586-020-2485-4

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice p.830

doi: 10.1038/s41586-020-2312-y

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters p.834

doi: 10.1038/s41586-020-2342-5

A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue p.839

doi: 10.1038/s41586-020-2527-y

Signalling input from divergent pathways subverts B cell transformation p.845

doi: 10.1038/s41586-020-2513-4

Histone H3.3 phosphorylation amplifies stimulation-induced transcription p.852

doi: 10.1038/s41586-020-2533-0

DNA surface exploration and operator bypassing during target search p.858

doi: 10.1038/s41586-020-2413-7

Molecular basis of β-arrestin coupling to formoterol-bound β₁-adrenoceptor p.862

doi: 10.1038/s41586-020-2419-1