UK and EU: Cherish what you have achieved and stay close p.597

doi: 10.1038/d41586-020-00226-x

What you want Nature to do next p.598

We asked readers what we should focus on in the next decade. Here is what you said.

doi: 10.1038/d41586-020-00227-w

China coronavirus: Six questions scientists are asking p.605

Researchers are racing to find out more about the epidemiology and genetic sequence of the coronavirus spreading in Asia and beyond.

doi: 10.1038/d41586-020-00166-6

This scientist hopes to test coronavirus drugs on animals in locked-down Wuhan p.607

doi: 10.1038/d41586-020-00190-6

Brexit is happening: what does it mean for science? p.608

doi: 10.1038/d41586-020-00215-0

The battle for ethical AI at the world’s biggest machine-learning conference p.609

Bias and the prospect of societal harm increasingly plague artificial-intelligence research — but it’s not clear who should be on the lookout for these problems.

doi: 10.1038/d41586-020-00160-y

The race to decipher how climate change influenced Australia’s record fires p.610

doi: 10.1038/d41586-020-00173-7

How the stress of fight or flight turns hair white p.623

Signalling from the sympathetic nervous system of mice when subjected to stress leads to the depletion of a stem-cell population in their hair follicles. This discovery sheds light on why stress turns hair prematurely grey.

doi: 10.1038/d41586-019-03949-8

Suspect that modulates the heartbeat is ensnared p.624

The activity of calcium channels in the heart increases during what is called the fight-or-flight response. An investigation into the 50-year-old mystery of how this occurs has captured a previously overlooked suspect.

doi: 10.1038/d41586-020-00096-3

A milestone in the hunt for metallic hydrogen p.626

doi: 10.1038/d41586-020-00149-7

A watershed moment for protein structure prediction p.627

Two threads of research in the quest for methods that predict the 3D structures of proteins from their amino-acid sequences have become fully intertwined. The result is a leap forward in the accuracy of predictions.

doi: 10.1038/d41586-019-03951-0

Techniques converge to map the developing human heart at single-cell level p.629

Three methods for gene-expression profiling have now been combined to produce spatially defined single-cell maps of developing human organs from limited sample material, overcoming a major hurdle in studying human development.

doi: 10.1038/d41586-020-00151-z

Synchrotron infrared spectroscopic evidence of the probable transition to metal hydrogen p.631

doi: 10.1038/s41586-019-1927-3

Dualities and non-Abelian mechanics p.636

doi: 10.1038/s41586-020-1932-6

Fully hardware-implemented memristor convolutional neural network p.641

doi: 10.1038/s41586-020-1942-4

Gram-scale bottom-up flash graphene synthesis p.647

doi: 10.1038/s41586-020-1938-0

Redox-switchable carboranes for uranium capture and release p.652

doi: 10.1038/s41586-019-1926-4

Lactonization as a general route to β-C(sp³)–H functionalization p.656

doi: 10.1038/s41586-019-1859-y

Ocean forcing of penultimate deglacial and last interglacial sea-level rise p.660

doi: 10.1038/s41586-020-1931-7

Ancient West African foragers in the context of African population history p.665

doi: 10.1038/s41586-020-1929-1

A distributional code for value in dopamine-based reinforcement learning p.671

doi: 10.1038/s41586-019-1924-6

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells p.676

doi: 10.1038/s41586-020-1935-3

Host-mediated ubiquitination of a mycobacterial protein suppresses immunity p.682

doi: 10.1038/s41586-019-1915-7

VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours p.689

doi: 10.1038/s41586-019-1912-x

Mechanism of adrenergic Ca_V1.2 stimulation revealed by proximity proteomics p.695

doi: 10.1038/s41586-020-1947-z

Negative supercoil at gene boundaries modulates gene topology p.701

doi: 10.1038/s41586-020-1934-4

Improved protein structure prediction using potentials from deep learning p.706

doi: 10.1038/s41586-019-1923-7

Structure of SAGA and mechanism of TBP deposition on gene promoters p.711

doi: 10.1038/s41586-020-1944-2

Structure of the transcription coactivator SAGA p.717

doi: 10.1038/s41586-020-1933-5