Act now and avert a climate crisis p.309

Nature joins more than 250 media outlets in Covering Climate Now, a unique collaboration to focus attention on the need for urgent action.

doi: 10.1038/d41586-019-02734-x

How to make computing more sustainable p.310

doi: 10.1038/d41586-019-02781-4

End the drought in drought research p.310

Policymakers battling water shortages and land degradation need independent scientific advice.

doi: 10.1038/d41586-019-02782-3

Meet the weather observers on climate change’s front lines p.317

From Death Valley to Antarctica, the science of temperature records is hotting up as the planet warms.

doi: 10.1038/d41586-019-02632-2

‘Ecological grief’ grips scientists witnessing Great Barrier Reef’s decline p.318

Studying ecosystems affected by climate change takes an emotional toll on researchers.

doi: 10.1038/d41586-019-02656-8

African nations push UN to improve drought research p.319

Early-warning systems to identify areas at risk top countries’ wishlist.

doi: 10.1038/d41586-019-02760-9

Dramatic sea-ice melt caps tough Arctic summer p.320

From raging wildfires to melting ice in Greenland, the top of the world is screaming for help.

doi: 10.1038/d41586-019-02653-x

Giant ‘bubbles’ spotted around Milky Way’s black hole p.322

First major result from South Africa’s pioneering MeerKAT radiotelescope reveals remnants of energetic explosions at Galaxy’s centre.

doi: 10.1038/d41586-019-02726-x

The hard truths of climate change — by the numbers p.324

doi: 10.1038/d41586-019-02711-4

Where climate cash is flowing and why it’s not enough p.328

doi: 10.1038/d41586-019-02712-3

Debating the bedrock of climate-change mitigation scenarios p.348

Researchers and policymakers rely on computer simulations called integrated assessment models to determine the best strategies for tackling climate change. Here, scientists present opposing views on the suitability of these simulations.

doi: 10.1038/d41586-019-02744-9

Human embryo implantation modelled in microfluidic channels p.350

An innovative microfluidic device has enabled the modelling of the events that occur in human embryos when they implant in the wall of the uterus. It could be used to help understand early pregnancy loss.

doi: 10.1038/d41586-019-02563-y

Stochastic magnetic circuits rival quantum computing p.351

doi: 10.1038/d41586-019-02742-x

Survival skills ensure that cancer spreads p.353

How cancer cells migrate to a secondary site and become established there is not fully understood. An analysis of mouse and human cancer cells could help settle the debate about the role of the protein E-cadherin in this process.

doi: 10.1038/d41586-019-02570-z

Spectacularly rapid and regular X-ray eruptions observed from an active galaxy p.354

A galaxy has been seen producing strong, regular bursts of X-rays that recur on timescales of hours. The eruptions imply that the matter flowing onto the galaxy’s central black hole undergoes repeated restructuring.

doi: 10.1038/d41586-019-02652-y

A key to unlocking chromatin revealed by complex structures p.355

Histone proteins pack DNA into a condensed form called chromatin. Detailed structures of the MLL family of histone-modifying protein complexes have been defined, shedding light on how they operate.

doi: 10.1038/d41586-019-02593-6

A new scenario logic for the Paris Agreement long-term temperature goal p.357

doi: 10.1038/s41586-019-1541-4

A national experiment reveals where a growth mindset improves achievement p.364

doi: 10.1038/s41586-019-1466-y

Temporal plasticity of apical progenitors in the developing mouse neocortex p.370

doi: 10.1038/s41586-019-1515-6

A unified mechanicm for intron and exon definition and back-splicing p.375

doi: 10.1038/s41586-019-1523-6

Nine-hour X-ray quasi-periodic eruptions from a low-mass black hole galactic nucleus p.381

doi: 10.1038/s41586-019-1556-x

Quantum critical behaviour at the many-body localization transition p.385

doi: 10.1038/s41586-019-1527-2

Integer factorization using stochastic magnetic tunnel junctions p.390

doi: 10.1038/s41586-019-1557-9

Intrinsically stable organic solar cells under high-intensity illumination p.394

doi: 10.1038/s41586-019-1544-1

Hindered dialkyl ether synthesis with electrogenerated carbocations p.398

doi: 10.1038/s41586-019-1539-y

Rapid expansion of Greenland’s low-permeability ice slabs p.403

doi: 10.1038/s41586-019-1550-3

Climate and air-quality benefits of a realistic phase-out of fossil fuels p.408

doi: 10.1038/s41586-019-1554-z

Death march of a segmented and trilobate bilaterian elucidates early animal evolution p.412

doi: 10.1038/s41586-019-1522-7

Genome architecture and stability in the Saccharomyces cerevisiae knockout collection p.416

doi: 10.1038/s41586-019-1549-9

Controlled modelling of human epiblast and amnion development using stem cells p.421

doi: 10.1038/s41586-019-1535-2

Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells p.426

doi: 10.1038/s41586-019-1531-6

Targeting cardiac fibrosis with engineered T cells p.430

doi: 10.1038/s41586-019-1546-z

SLC19A1 transports immunoreactive cyclic dinucleotides p.434

doi: 10.1038/s41586-019-1553-0

E-cadherin is required for metastasis in multiple models of breast cancer p.439

doi: 10.1038/s41586-019-1526-3

Structural basis of nucleosome recognition and modification by MLL methyltransferases p.445

doi: 10.1038/s41586-019-1528-1