Volume 572 Issue 7769


Teenage activists and an IPCC triumph p.283

The latest report from the Intergovernmental Panel on Climate Change is a well-timed blueprint for action. Decision makers must now pay attention — a nascent youth movement is showing them how.

doi: 10.1038/d41586-019-02425-7


News Features

News & Views

Cancer-cell death ironed out p.314

Ferroptosis is a form of cell death. The finding that cells that have certain mutations in the Hippo signalling pathway are susceptible to ferroptosis might offer a way to treat a cancer called mesothelioma.

doi: 10.1038/d41586-019-02218-y

No bacteria found in healthy placentas p.317

Analysis of hundreds of placentas provides convincing evidence that this organ does not harbour microorganisms that can enter the fetal gut — a key finding for research into how the human microbiota is established.

doi: 10.1038/d41586-019-02262-8

How plants perceive salt p.318

High salt levels in the soil harm plant growth and limit crop yields. A salt-binding membrane lipid has been identified as being essential for salt perception and for triggering calcium signals that lead to salt tolerance.

doi: 10.1038/d41586-019-02289-x

A dynamic view of chemotherapy effectiveness p.321

Chemotherapy can halt cancer by causing cells to enter a non-dividing state called senescence, but sometimes it causes tumour cells to proliferate. It now seems that the dynamics of the protein p21 governs which of these fates occurs.

doi: 10.1038/d41586-019-02336-7