Teenage activists and an IPCC triumph p.283

The latest report from the Intergovernmental Panel on Climate Change is a well-timed blueprint for action. Decision makers must now pay attention — a nascent youth movement is showing them how.

doi: 10.1038/d41586-019-02425-7

Eat less meat: UN climate-change report calls for change to human diet p.291

The report on global land use and agriculture comes amid accelerating deforestation in the Amazon.

doi: 10.1038/d41586-019-02409-7

Astronomy impasse: What's next for the Thirty Meter Telescope? p.292

Protestors in Hawaii have prevented construction for more than three weeks, and there is no sign of a resolution in sight.

doi: 10.1038/d41586-019-02354-5

Scientists glimpse oddball microbe that could help explain rise of complex life p.294

‘Lokiarchaea’, previously known only from DNA, is isolated and grown in culture.

doi: 10.1038/d41586-019-02430-w

Mexican science suffers under debilitating budget cuts p.294

Some researchers have turned to crowdfunding campaigns to pay for supplies and several scientific institutes are rationing electricity to save money.

doi: 10.1038/d41586-019-02332-x

Dark-energy mapper will reconstruct 11 billion years of cosmic history p.295

A telescope in Arizona will conduct the largest spectroscopic survey of galaxies.

doi: 10.1038/d41586-019-02424-8

The quest to unlock the secrets of the baby Universe p.298

doi: 10.1038/d41586-019-02417-7

Cancer-cell death ironed out p.314

Ferroptosis is a form of cell death. The finding that cells that have certain mutations in the Hippo signalling pathway are susceptible to ferroptosis might offer a way to treat a cancer called mesothelioma.

doi: 10.1038/d41586-019-02218-y

Signs that Jupiter was mixed by a giant impact p.315

doi: 10.1038/d41586-019-02401-1

No bacteria found in healthy placentas p.317

Analysis of hundreds of placentas provides convincing evidence that this organ does not harbour microorganisms that can enter the fetal gut — a key finding for research into how the human microbiota is established.

doi: 10.1038/d41586-019-02262-8

How plants perceive salt p.318

High salt levels in the soil harm plant growth and limit crop yields. A salt-binding membrane lipid has been identified as being essential for salt perception and for triggering calcium signals that lead to salt tolerance.

doi: 10.1038/d41586-019-02289-x

X marks the spot for fast radio bursts p.320

doi: 10.1038/d41586-019-02400-2

A dynamic view of chemotherapy effectiveness p.321

Chemotherapy can halt cancer by causing cells to enter a non-dividing state called senescence, but sometimes it causes tumour cells to proliferate. It now seems that the dynamics of the protein p21 governs which of these fates occurs.

doi: 10.1038/d41586-019-02336-7

Exome sequencing of Finnish isolates enhances rare-variant association power p.323

doi: 10.1038/s41586-019-1457-z

Human placenta has no microbiome but can contain potential pathogens p.329

doi: 10.1038/s41586-019-1451-5

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy p.335

doi: 10.1038/s41586-019-1406-x

Plant cell-surface GIPC sphingolipids sense salt to trigger Ca²⁺ influx p.341

doi: 10.1038/s41586-019-1449-z

Modulation of cardiac ryanodine receptor 2 by calmodulin p.347

doi: 10.1038/s41586-019-1377-y

A fast radio burst localized to a massive galaxy p.352

doi: 10.1038/s41586-019-1389-7

The formation of Jupiter’s diluted core by a giant impact p.355

doi: 10.1038/s41586-019-1470-2

Imaging magnetic polarons in the doped Fermi–Hubbard model p.358

doi: 10.1038/s41586-019-1463-1

Global entangling gates on arbitrary ion qubit p.363

doi: 10.1038/s41586-019-1428-4

Parallel entangling operations on a universal ion-trap quantum computer p.368

doi: 10.1038/s41586-019-1427-5

Committed emissions from existing energy infrastructure jeopardize 1.5°C climate target p.373

doi: 10.1038/s41586-019-1364-3

Metamorphism and the evolution of plate tectonics p.378

doi: 10.1038/s41586-019-1462-2

Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin catalysed glutamylation p.382

doi: 10.1038/s41586-019-1440-8

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase p.387

doi: 10.1038/s41586-019-1439-1

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy p.392

doi: 10.1038/s41586-019-1456-0

Dietary methionine influences therapy in mouse cancer models and alters human metabolism p.397

doi: 10.1038/s41586-019-1437-3

Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling p.402

doi: 10.1038/s41586-019-1426-6