An innovative way to publish p.447

The research community needs to find ways to reward study design and methodology as much as the final result. A publishing format called Registered Reports offers a means of addressing this challenge.

doi: 10.1038/d41586-019-02277-1

Write rules for deep-sea mining before it’s too late p.447

The International Seabed Authority must commit the mining industry to a sustainable future.

doi: 10.1038/d41586-019-02276-2

Ocean snail is first animal to be officially endangered by deep-sea mining p.455

Valuable metals and minerals pepper the creature's habitat, drawing commercial interest to the sea floor.

doi: 10.1038/d41586-019-02231-1

Depression researchers rethink popular mouse swim tests p.456

Animal-rights group’s campaign to end forced-swim tests comes amid debate over whether method is overused.

doi: 10.1038/d41586-019-02133-2

New EU chief makes bold climate pledges p.457

Ursula von der Leyen’s ambitions to strengthen carbon-cutting goals will need support from European Union member states.

doi: 10.1038/d41586-019-02204-4

How fast is the Universe expanding? Cosmologists just got more confused p.458

Hotly anticipated technique fails to resolve disagreement over speed of cosmic expansion — for now.

doi: 10.1038/d41586-019-02198-z

Hallucinations implanted in mouse brains using light p.459

Behavioural evidence suggests that targeting just 20 neurons prompted animals to ‘see’ an image.

doi: 10.1038/d41586-019-02220-4

How a data detective exposed suspicious medical trials p.462

doi: 10.1038/d41586-019-02241-z

Seabed mining is coming — bringing mineral riches and fears of epic extinctions p.465

doi: 10.1038/d41586-019-02242-y

Counting grains of sound p.480

doi: 10.1038/d41586-019-02233-z

Infection triggers symptoms similar to those of Parkinson’s disease in mice lacking PINK1 protein p.481

In mice lacking a protein genetically linked to Parkinson’s disease, an autoimmune response to gut infection compromises the function of dopamine-producing neurons and leads to transient movement impairments.

doi: 10.1038/d41586-019-02094-6

The aberrant global synchrony of present-day warming p.483

doi: 10.1038/d41586-019-02179-2

Cell communication in the blink of an eye p.484

The bodies of unicellular organisms called protists can contract extremely fast. Analysis reveals that the flow of surrounding fluid during contraction triggers a chain reaction of contraction of neighbouring protists.

doi: 10.1038/d41586-019-02069-7

Marine heatwaves in a changing climate p.485

Heatwaves in the ocean can rapidly disrupt marine ecosystems and the economies that depend on them. A global analysis of these events casts light on their causes and sets the stage for revealing how they might change in the future.

doi: 10.1038/d41586-019-02196-1

An early dispersal of modern humans from Africa to Greece p.487

Analysis of two fossils from a Greek cave has shed light on early hominins in Eurasia. One fossil is the earliest known specimen of Homo sapiens found outside Africa; the other is a Neanderthal who lived 40,000 years later.

doi: 10.1038/d41586-019-02075-9

Advances in epigenetics link genetics to the environment and disease p.489

doi: 10.1038/s41586-019-1411-0

Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia p.500

doi: 10.1038/s41586-019-1376-z

Gene expression across mammalian organ development p.505

doi: 10.1038/s41586-019-1338-5

Developmental dynamics of lncRNAs across mammalian organs and species p.510

doi: 10.1038/s41586-019-1341-x

H⁺ transport is an integral function of the mitochondrial ADP/ATP carrier p.515

doi: 10.1038/s41586-019-1400-3

Isomerization of BRCA1–BARD1 promotes replication fork protection p.521

doi: 10.1038/s41586-019-1363-4

General relativistic orbital decay in a seven-minute-orbital-period eclipsing binary system p.528

doi: 10.1038/s41586-019-1403-0

Interacting Floquet polaritons p.532

doi: 10.1038/s41586-019-1354-5

Resolving the energy levels of a nanomechanical oscillator p.537

doi: 10.1038/s41586-019-1386-x

A strongly inhomogeneous superfluid in an iron-based superconductor p.541

doi: 10.1038/s41586-019-1408-8

Peptide ligation by chemoselective aminonitrile coupling in water p.546

doi: 10.1038/s41586-019-1371-4

No evidence for globally coherent warm and cold periods over the preindustrial Common Era p.550

doi: 10.1038/s41586-019-1401-2

Deep hydrous mantle reservoir provides evidence for crustal recycling before 3.3 billion years ago p.555

doi: 10.1038/s41586-019-1399-5

Collective intercellular communication through ultra-fast hydrodynamic trigger waves p.560

doi: 10.1038/s41586-019-1387-9

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice p.565

In mice lacking PINK1, bacterial infection in the intestine results in mitochondrial antigen presentation and generation of CD8+ T cells, and infected mice develop motor impairments, suggesting that PINK1 suppresses autoimmunity.

doi: 10.1038/s41586-019-1405-y

Immune evasion before tumour invasion in early lung squamous carcinogenesis p.570

doi: 10.1038/s41586-019-1330-0

Tumour lineage shapes BRCA-mediated phenotypes p.576

doi: 10.1038/s41586-019-1382-1

Conformation space of a heterodimeric ABC exporter under turnover conditions p.580

doi: 10.1038/s41586-019-1391-0