To contain Ebola, the United States must fulfil its promise to the World Health Organization p.145

WHO responders are braving bullets to end the outbreak in the Democratic Republic of the Congo, but the virus could cross borders without the pledged funding.

doi: 10.1038/d41586-019-02118-1

Cancer, climate, plastics: why ‘earthshots’ are harder than moonshots p.145

doi: 10.1038/d41586-019-02093-7

Can NASA really return people to the Moon by 2024? p.153

Donald Trump wants US astronauts back on the Moon. But his ambitious plan faces formidable political, financial and technical challenges.

doi: 10.1038/d41586-019-02020-w

Climate change made Europe’s mega-heatwave five times more likely p.155

Scientists rushed to study whether the scorching temperatures last week were linked to global warming.

doi: 10.1038/d41586-019-02071-z

NASA changes how it divvies up telescope time to reduce gender bias p.156

The switch to double-blind peer review will affect roughly 650 scientists working on projects worth an estimated US$55 million.

doi: 10.1038/d41586-019-02064-y

‘Psychological fear’: MIT scientists of Chinese origin protest toxic US climate p.157

Researchers describe how a government crackdown on foreign influence is affecting them following a statement of support from their university.

doi: 10.1038/d41586-019-02063-z

Scandal-weary Swedish government takes over research-fraud investigations p.158

The Research Misconduct Board is one of the first national agencies tasked with investigating serious research misconduct.

doi: 10.1038/d41586-018-05493-3

Self-destructing mosquitoes and sterilized rodents: the promise of gene drives p.160

doi: 10.1038/d41586-019-02087-5

These young scientists will shape the next 50 years of Moon research p.163

doi: 10.1038/d41586-019-02086-6

Walking on your sensitive sole p.176

Thick foot calluses develop naturally when walking barefoot. It emerges that they preserve foot sensitivity while offering protection, thus avoiding the trade-off between the two that occurs with cushioned shoes.

doi: 10.1038/d41586-019-01953-6

Low retention of impact material by the Moon p.177

doi: 10.1038/d41586-019-02066-w

Infiltration of old brains by T cells causes dysfunction of neural stem cells p.178

Age-dependent changes in their environment can impair stem cells’ function. The finding that T cells infiltrate the brains of aged mice and cause dysfunction of neural stem cells reveals a potential therapeutic target.

doi: 10.1038/d41586-019-01832-0

Hijack of CRISPR defences by selfish genes holds clinical promise p.180

Parasitic genetic elements called transposons carry CRISPR machinery that is normally used against them by bacterial cells. This paradox has now been explained, with implications for gene-therapy research.

doi: 10.1038/d41586-019-01824-0

Fishing out a feeding paradox p.181

If an animal’s body shape is specialized in a way that aids feeding on specific organisms, does this restrict what the animal can prey on? An observation of fishes feeding in the wild might now help to settle this question.

doi: 10.1038/d41586-019-02008-6

From discoveries in ageing research to therapeutics for healthy ageing p.183

doi: 10.1038/s41586-019-1365-2

Climate as a risk factor for armed conflict p.193

doi: 10.1038/s41586-019-1300-6

Neural signatures of sleep in zebrafish p.198

doi: 10.1038/s41586-019-1336-7

Single-cell analysis reveals T cell infiltration in old neurogenic niches p.205

doi: 10.1038/s41586-019-1362-5

TOX transcriptionally and epigenetically programs CD8⁺ T cell exhaustion p.211

doi: 10.1038/s41586-019-1325-x

Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration p.219

doi: 10.1038/s41586-019-1323-z

Reconstructing the late-accretion history of the Moon p.226

doi: 10.1038/s41586-019-1359-0

Tracking the precession of single nuclear spins by weak measurements p.230

doi: 10.1038/s41586-019-1334-9

Magnetic monopole noise p.234

doi: 10.1038/s41586-019-1358-1

Light-wave dynamic control of magnetism p.240

doi: 10.1038/s41586-019-1333-x

Planar perovskite solar cells with long-term stability using ionic liquid additives p.245

doi: 10.1038/s41586-019-1357-2

Controlling protein assembly on inorganic crystals through designed protein interfaces p.251

doi: 10.1038/s41586-019-1361-6

National food production stabilized by crop diversity p.257

doi: 10.1038/s41586-019-1316-y

Foot callus thickness does not trade off protection for tactile sensitivity during walking p.261

doi: 10.1038/s41586-019-1345-6

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection p.265

doi: 10.1038/s41586-019-1326-9

TOX is a critical regulator of tumour-specific T cell differentiation p.270

doi: 10.1038/s41586-019-1324-y

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis p.275

doi: 10.1038/s41586-019-1314-0

Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric G_i p.279

doi: 10.1038/s41586-019-1286-0

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity p.284

doi: 10.1038/s41586-019-1355-4