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Volume 565 Issue 7738

Editorials

Save the whales, again p.133

Japan’s sudden exit from the International Whaling Commission presents an opportunity for a fresh start, and a larger role for science.

doi: 10.1038/d41586-019-00076-2

News

News Features

News & Views

Unprovability comes to machine learning p.166

Scenarios have been discovered in which it is impossible to prove whether or not a machine-learning algorithm could solve a particular problem. This finding might have implications for both established and future learning algorithms.

doi: 10.1038/d41586-019-00012-4

Fat cells with a sweet tooth p.167

Some fat cells convert energy into heat, so targeting them to induce weight loss is appealing. The discovery that a subset of the cells burns glucose, rather than both glucose and lipids, could improve our ability to do just that.

doi: 10.1038/d41586-018-07739-6

Immune cells track hard-to-target brain tumours p.170

Clinical trials reveal that personalized vaccines can boost immune-cell responses to brain tumours that don’t usually respond to immunotherapy. The findings also point to how to improve such treatments.

doi: 10.1038/d41586-018-07728-9

Articles

Letters