Reform the Antarctic Treaty p.161
Political protection for the planet’s last great wilderness is no longer fit for purpose. Make its governance democratic: scrap the veto that lets individual interests rule.doi: 10.1038/d41586-018-05368-7
Volume 558 Issue 7709
리서치 하이라이트
표지 기사： 3D프린트를 통한 강자성 도메인 인쇄 및 이를 통한 고속 형태 변형 소프트 재료 구현
유럽 숲에서 외균근류의 다양성 및 분포에 큰 영향을 주는 외부 환경 및 숙주 특이성
사람 40S 리보솜 서브유닛의 완성에 대한 후기 단계 구조 가시화
LRRC8 단백질 계열의 음이온 채널 구조 분석
4개의 먼지 은하계에서 거대 별 형성이 우세하였다는 것을 입증하는 13C/18O 방사선동위원소 비율
마이크로웨이브 광자를 이용한 양자 상태 전송 및 원격 얽힘 조절
지난 8백만 년 동안 거의 쇠퇴하지 않은 남극 동부 지역 대륙빙
인지질 산화와 동맥경화증 과의 상관관계 확인
TET2의 기능 억제를 통한 CD19 CAR-T세포의 항암 효능 증대
컨텐츠
Editorials
The phrase ‘necessary and sufficient’ blamed for flawed neuroscience p.162
Muddled language can lead scientists in the wrong direction, neurobiologists claim.doi: 10.1038/d41586-018-05418-0
China sets a strong example on how to address scientific fraud p.162
New measures introduce what could be the world’s strongest disincentive for misconduct so far.doi: 10.1038/d41586-018-05417-1
News
FARC and the forest: Peace is destroying Colombia’s jungle — and opening it to science p.169
As loggers and miners move into previously inaccessible regions, researchers are pooling knowledge about the country’s ecosystems.doi: 10.1038/d41586-018-05397-2
China introduces sweeping reforms to crack down on academic misconduct p.171
Initiatives include a national list of cases, a blacklist of ‘poor quality’ journals and a government agency that is responsible for policing misconduct.doi: 10.1038/d41586-018-05359-8
Speedy Ebola tests help contain Africa’s latest outbreak p.172
Health workers battling Ebola in the Democratic Republic of the Congo can diagnose the virus in hours, instead of days.doi: 10.1038/d41586-018-05389-2
Sucking carbon dioxide from air is cheaper than scientists thought p.173
Estimated cost of geoengineering technology to fight climate change has plunged since a 2011 analysis.doi: 10.1038/d41586-018-05357-w
Faecal transplants could help preserve vulnerable species p.173
New gut bacteria can expand the diet of animals like koalas and rhinoceroses.doi: 10.1038/d41586-018-05352-1
News Features
The battle behind the periodic table’s latest additions p.175
Four new elements were added in 2015 with great fanfare — but some researchers complain the announcement was premature.doi: 10.1038/d41586-018-05371-y
News & Views
On-demand entanglement could lead to scalable quantum networks p.192
Two experiments show that non-classical correlations can be distributed between distant nodes of a quantum network in a deterministic way. The work smooths the path for extended quantum networks.doi: 10.1038/d41586-018-05336-1
Tumour tamed by transfer of one T cell p.193
The T cells of the immune system can be engineered to target a tumour, but why some people respond better than others to such therapy is unclear. One patient’s striking response to treatment now offers some clues.doi: 10.1038/d41586-018-05251-5
Enzymes can adapt to cold by wiggling regions far from their active site p.195
Mutations introduced far from the active site of an enzyme can cause local unfolding that increases enzyme activity. This finding suggests how organisms that live in the cold can speed up biochemical reactions.doi: 10.1038/d41586-018-05302-x
How humans and rising seas affect each other p.196
The Paris climate agreement aims to limit global warming to no more than 2 °C. An analysis suggests that this will greatly reduce the risks of sea-level rise for coastal communities, but that it will take time to see the benefit.doi: 10.1038/d41586-018-05366-9
Transcription regulation enters a new phase p.197
A subunit of the enzymatic complex P-TEFb can induce compartmentalization of proteins into liquid-like droplets in cells. This phase separation might help P-TEFb to promote gene transcription.doi: 10.1038/d41586-018-05244-4
Articles
Environment and host as large-scale controls of ectomycorrhizal fungi p.243
Analyses of data from 137 forest plots across 20 European countries show that ectomycorrhizal fungal diversity is strongly influenced by environmental and host species factors and provide thresholds to inform ecosystem assessment toolsdoi: 10.1038/s41586-018-0189-9
Visualizing late states of human 40S ribosomal subunit maturation p.249
Cryo-EM structures of late intermediates in the assembly of human 40S ribosomal subunits help to define the principles by which immature rRNA conformations and ribosomal biogenesis factors shape the 40S maturation process.doi: 10.1038/s41586-018-0193-0
Structure of a volume-regulated anion channel of the LRRC8 family p.254
The structure of a homomeric channel of subunit A of leucine-rich repeat-containing protein 8 (LRRC8) determined by cryo-electron microscopy and X-ray crystallography reveals the basis for anion selectivity.doi: 10.1038/s41586-018-0134-y
Letters
Stellar populations dominated by massive stars in dusty starburst galaxies across cosmic time p.260
Observations of 13CO and C18O emission from four dusty starburst galaxies at redshifts of approximately two to three reveal that massive stars are more numerous in starburst events than in ordinary star-forming spiral galaxies.doi: 10.1038/s41586-018-0196-x
Deterministic quantum state transfer and remote entanglement using microwave photons p.264
Deterministic quantum state transfer and entanglement generation is demonstrated between superconducting qubits on distant chips using single photons.
doi: 10.1038/s41586-018-0195-y
Deterministic delivery of remote entanglement on a quantum network p.268
Remote deterministic spin–spin entanglement is achieved using nitrogen–vacancy centres in diamonds and a single-photon entangling protocol, with much improved entangling rates compared to previously used two-photon protocols.doi: 10.1038/s41586-018-0200-5
Printing ferromagnetic domains for untethered fast-transforming soft materials p.274
Programmed ferromagnetic domains are 3D-printed into soft materials capable of fast transformations between complex three-dimensional shapes via magnetic actuation.doi: 10.1038/s41586-018-0185-0
Velocity-resolved kinetics of site-specific carbon monoxide oxidation on platinum surfaces p.280
The catalytic oxidation of carbon monoxide over platinum proceeds through two distinct channels: it is dominated at low temperatures by the more active step sites and at high temperatures by the more abundant terrace sites of the platinum surface.doi: 10.1038/s41586-018-0188-x
Minimal East Antarctic Ice Sheet retreat onto land during the past eight million years p.284
Analysis of cosmogenic isotopes from a marine sediment core shows that much of the land-based East Antarctic Ice Sheet has remained stable for the past eight million years, including during the warm Pliocene epoch.doi: 10.1038/s41586-018-0155-6
Rapid recovery of life at ground zero of the end-Cretaceous mass extinction p.288
Micro- and nannofossil, trace fossil and geochemical evidence from the Chicxulub impact crater demonstrates that proximity to the asteroid impact site did not determine rates of recovery of marine ecosystems after the end-Cretaceous mass extinction.doi: 10.1038/s41586-018-0163-6
Parallel emergence of stable and dynamic memory engrams in the hippocampus p.292
Imaging of hippocampal neuron activity in mice performing a memory task across several days identifies both stable and dynamic memory engrams.doi: 10.1038/s41586-018-0191-2
A molecular rheostat adjusts auxin flux to promote root protophloem differentiation p.297
The coordinated action of BREVIS RADIX (BRX) and PROTEIN KINASE ASSOCIATED WITH BRX (PAX) regulates auxin flux during the development of protophloem sieve elements in the root meristem of Arabidopsis.doi: 10.1038/s41586-018-0186-z
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice p.301
A single-chain variable fragment of the antibody E06, which binds to the phosphocholine headgroup of oxidized phospholipids, blocks the uptake of oxidized low-density lipoprotein by macrophages, and reduces inflammation and atherosclerosis in hypercholesterolaemic mice.doi: 10.1038/s41586-018-0198-8
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells p.307
Genetically engineered T cells that induced remission in a patient with chronic lymphocytic leukaemia were found to have disruption of thedoi: 10.1038/s41586-018-0178-z
EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle p.313
The transition between early mitotic inhibitor 1 acting as a substrate of the APC/C and as an inhibitor of the same complex results in an irreversible switch that mediates human cell-cycle commitment.doi: 10.1038/s41586-018-0199-7
Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II p.318
The histidine-rich domain of cyclin T1 promotes phase separation into liquid droplets, which facilitates the hyperphosphorylation of the C-terminal domain repeats of RNA polymerase II.doi: 10.1038/s41586-018-0174-3
Dynamic allostery can drive cold adaptation in enzymes p.324
By engineering entropy-tuning changes into distal sites of a bacterial adenylate kinase, an allosteric tuning mechanism based on protein dynamics is revealed.doi: 10.1038/s41586-018-0183-2
