Editorials
Improving the participation of under-represented groups is not just fairer — it could produce better research.
doi: 10.1038/d41586-018-05326-3
Therapies tailored to individual tumours must not be oversold.
doi: 10.1038/d41586-018-05323-6
Report on plant protection highlights the fragmented nature of current decision-making on agriculture.
doi: 10.1038/d41586-018-05327-2
News
They say the Max Planck Society’s reaction to the indictment of Nikos Logothetis has disrupted research.
doi: 10.1038/d41586-018-05187-w
Independent board will review agency decisions to repeal or change climate regulations and rules on the use of non-public data.
doi: 10.1038/d41586-018-05319-2
Storms' slowdown means more rain, and potentially more damage, for populated areas.
doi: 10.1038/d41586-018-05324-5
The European Research Council publishes its third annual impact assessment of the projects it funds.
doi: 10.1038/d41586-018-05325-4
Award goes to biochemists Virginijus Siksnys, whose lab independently developed the gene-editing tool, Emmanuelle Charpentier and Jennifer Doudna.
doi: 10.1038/d41586-018-05308-5
News Features
Being inclusive gives research groups a competitive edge. It also happens to be the right thing to do.
doi: 10.1038/d41586-018-05316-5
News & Views
The unexpected discovery of a nearly complete skull from the Early Cretaceous epoch that has been preserved in three dimensions provides profound insights into the evolution and biogeography of early mammals.
doi: 10.1038/d41586-018-05134-9
An avalanche of data is about to revolutionize astronomy, but the options for validating those data have been limited. High-precision measurements from the Hubble Space Telescope enable a much-needed alternative option.
doi: 10.1038/d41586-018-05306-7
An embryo’s body plan is established by a structure called the organizer. Evidence of this structure in humans has been lacking, but a stem-cell-based protocol has now enabled researchers to demonstrate its existence.
doi: 10.1038/d41586-018-05115-y
The speed at which tropical cyclones travel has slowed globally in the past seven decades, especially over some coastlines. This effect can compound flooding by increasing regional total rainfall from storms.
doi: 10.1038/d41586-018-05303-w
Recordings of individual neurons in the mouse brain reveal a main mechanism for motion processing in the primary visual cortex. These findings are likely to have implications for other species.
doi: 10.1038/d41586-018-04289-9
Emerging nanoelectronic devices could revolutionize artificial neural networks, but their hardware implementations lag behind those of their software counterparts. An approach has been developed that tips the scales in their favour.
doi: 10.1038/d41586-018-05297-5
Review
A Review of the cues and mechanisms used by animals to navigate over long distances, with a particular emphasis on magnetoreception.
doi: 10.1038/s41586-018-0176-1
Perspective
The results of efforts to limit global mean warming to below 1.5 °C may include many possible future world climates.
doi: 10.1038/s41586-018-0181-4
Articles
Analogue-memory-based neural-network training using non-volatile-memory hardware augmented by circuit simulations achieves the same accuracy as software-based training but with much improved energy efficiency and speed.
doi: 10.1038/s41586-018-0180-5
An approach using multiple stable isotopes reveals that early tetrapods of the Devonian period were euryhaline animals that inhabited aquatic environments of highly variable salinity.
doi: 10.1038/s41586-018-0159-2
A genetic atlas of the human plasma proteome, comprising 1,927 genetic associations with 1,478 proteins, identifies causes of disease and potential drug targets.
doi: 10.1038/s41586-018-0175-2
Direction selectivity emerges de novo in layer 4 neurons of primary visual cortex through the convergence of synaptic inputs from thalamic neurons that respond with distinct time courses to visual stimuli in distinct locations.
doi: 10.1038/s41586-018-0148-5
Letters
Observations of broadband emission from lightning on Jupiter at 600 megahertz show a lightning discharge mechanism similar to that of terrestrial lightning and indicate increased moist convection near Jupiter’s poles.
doi: 10.1038/s41586-018-0156-5
Lattice quantum chromodynamics and a method inspired by the Feynman–Hellmann theorem are used to make a theoretical determination of the nucleon axial coupling with a precision of one per cent, giving the value 1.271 ± 0.013.
doi: 10.1038/s41586-018-0161-8
A ‘magneto-Peltier effect’ produces cooling or heating in a material without junctions, by forcing a change in angle between the current and magnetization in a single ferromagnetic nickel slab.
doi: 10.1038/s41586-018-0143-x
Less than 0.01 per cent by weight of water in an alkane solvent is sufficient to interact with co-dissolved supramolecular polymeric chains by hydrogen bonding and modulate the structure of the assembly.
doi: 10.1038/s41586-018-0169-0
The translation speed of tropical cyclones has decreased globally by 10% over the past 70 years, compounding the increases in cyclone-related local rainfall that have resulted from anthropogenic warming.
doi: 10.1038/s41586-018-0158-3
An exceptionally preserved skull of Cifelliodon wahkarmoosuch sheds light on the evolution of the ancestral mammalian brain.
doi: 10.1038/s41586-018-0126-y
The urban-heat-island effect drives community-level shifts towards smaller body sizes; however, habitat fragmentation caused by urbanization favours larger body sizes in species with positive size–dispersal links.
doi: 10.1038/s41586-018-0140-0
Mutagenesis of a yeast tRNA shows that the effects of mutations and how they interact varies both in magnitude and sign between genotypes.
doi: 10.1038/s41586-018-0170-7
Shark and skate electrosensory cells use specific potassium channels to support either indiscriminate detection of electrical stimuli or selective frequency tuning, respectively, demonstrating adaptation of sensory systems through discrete molecular modifications.
doi: 10.1038/s41586-018-0160-9
The identity and hedonic value of tastes are encoded in distinct neural substrates; in mice, the amygdala is necessary and sufficient to drive valence-specific behaviours in response to bitter or sweet taste stimuli, and the cortex can independently represent taste identity.
doi: 10.1038/s41586-018-0165-4
Stimulation of Wnt and Nodal pathways in micropatterned human embryonic stem cell colonies induce these colonies to exhibit characteristic spatial expression patterns of the organizer and reproduce organizer function when grafted into a host embryo.
doi: 10.1038/s41586-018-0150-y
A knock-in mutation in beclin 1 that increases autophagy in mice extends animal lifespan, improves healthspan, and also rescues early lethality in mice deficient in the anti-ageing protein klotho.
doi: 10.1038/s41586-018-0162-7
A data-driven analysis helps to identify specific roles of the Hippo signalling kinases Mst1 and Mst2 in integrating metabolic activity and cytokine signalling in dendritic cells, and thereby orchestrating immune cell function.
doi: 10.1038/s41586-018-0177-0