Trump’s vaccine-commission idea is biased and dangerous p.259

Scientists must fight back with the truth about the debunked link between vaccines and autism.

doi: 10.1038/541259a

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Replication studies offer much more than technical details p.259

They demonstrate the practice of science at its best.

doi: 10.1038/541259b

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Base the social cost of carbon on the science p.260

The potential economic damage from global warming should not be influenced by politics.

doi: 10.1038/541260a

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India’s first GM food crop held up by lawsuit p.267

Scientists accused of deceiving the public about benefits of transgenic mustard.

Sanjay Kumar

doi: 10.1038/541267a

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Cancer reproducibility project releases first results p.269

An open-science effort to replicate dozens of cancer-biology studies is off to a confusing start.

Monya Baker & Elie Dolgin

doi: 10.1038/541269a

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Gates Foundation research can’t be published in top journals p.270

Publications such as Nature and Science have policies that clash with the global health charity's open-access mandate.

Richard Van Noorden

doi: 10.1038/nature.2017.21299

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Space-weather forecast to improve with European satellite p.271

Probe could give early warnings of catastrophic solar storms heading for Earth.

doi: 10.1038/541271a

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US energy agency strengthens protections for scientists p.272

Revised scientific-integrity policy gives researchers more leeway to speak to the press and publish their findings.

Erin Ross

doi: 10.1038/nature.2017.21290

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Croatia’s science minister rejects calls to resign amid plagiarism scandal p.272

Pavo Barišić says he won't step down after a parliamentary ethics committee found he copied another scholar's work.

Mićo Tatalović & Nenad Jarić Dauenhauer

doi: 10.1038/541272a

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News Features

宇宙探査: 火星へ

The $2.4-billion plan to steal a rock from Mars p.274

NASA is now building the rover that it hopes will bring back signs of life on the red planet.

doi: 10.1038/541274a

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遺伝学: CRISPRの謎

Five big mysteries about CRISPR’s origins p.280

Where did it come from? How do organisms use it without self-destructing? And what else can it do?

doi: 10.1038/541280a

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News & Views

量子光学: 時間的に静かな瞬間

Quantum optics: Quiet moments in time p.292

'Squeezed' light exhibits smaller quantum fluctuations than no light at all. Localized squeezed regions have now been produced along an infrared light wave and probed with unprecedented time resolution. See Letter p.376

Marco Bellini

doi: 10.1038/541292a

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分子生物学: メッセンジャーRNAの寿命を延ばす

Molecular biology: Messenger RNAs marked for longer life p.293

A molecular modification called m6Am has been found to regulate the stability of messenger RNAs in mammalian cells. The mechanism casts fresh light on how reversibly modified RNA bases control the fate of mRNA. See Article p.371

David E. Weinberg & John D. Gross

doi: 10.1038/nature21109

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人間行動学: 買物客はなじみのものを好む

Human behaviour: Shoppers like what they know p.294

Faced with ever-changing products, consumers can benefit from trying new items. But data collected over almost five years show that, the longer shoppers have been buying a favourite product, the more likely they are to stick with it.

Peter M. Todd

doi: 10.1038/nature21114

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再構成可能な材料: 折り紙構造のアルゴリズム

Reconfigurable materials: Algorithm for architectural origami p.296

An algorithm has been developed allowing the rational design of origami-inspired materials that can be rearranged to change their properties. This might open the way to strategies for making reconfigurable robots. See Article p.347

Jamie Paik

doi: 10.1038/541296a

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微生物学: 細胞進化のギャップを埋める

Microbiology: Mind the gaps in cellular evolution p.297

Eukaryotic cells, with complex features such as membrane-bound nuclei, evolved from prokaryotic cells that lack these components. A newly identified prokaryotic group reveals intermediate steps in eukaryotic-cell evolution. See Article p.353

James O. McInerney & Mary J. O'Connell

doi: 10.1038/nature21113

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ウイルス学: ピコルナウイルスの侵入と排除

Virology: Ins and outs of picornaviruses p.299

Competition between the phospholipase enzyme PLA2G16 and the protein galectin-8 determines whether the RNA-based genomes of picornaviruses can be effectively delivered into host cells. See Letter p.412

Kevin L. McKnight & Stanley M. Lemon

doi: 10.1038/nature21116

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材料科学: 再構成可能に構造設計された角柱状材料の合理的な設計

Rational design of reconfigurable prismatic architected materials p.347

Johannes T. B. Overvelde, James C. Weaver, Chuck Hoberman & Katia Bertoldi

doi: 10.1038/nature20824

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微生物学: Asgard上門アーキアによって明らかになる真核細胞の複雑性の起源

Asgard archaea illuminate the origin of eukaryotic cellular complexity p.353

Katarzyna Zaremba-Niedzwiedzka, Eva F. Caceres, Jimmy H. Saw, Disa Bäckström, Lina Juzokaite, Emmelien Vancaester, Kiley W. Seitz, Karthik Anantharaman, Piotr Starnawski, Kasper U. Kjeldsen + et al.

doi: 10.1038/nature21031

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がん: 非緩慢性限局性前立腺がんのゲノムの特徴

Genomic hallmarks of localized, non-indolent prostate cancer p.359

Michael Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, Lawrence E. Heisler, Julie Livingstone, Vincent Huang, Yu-Jia Shiah, Fouad Yousif, Xihui Lin, Andre P. Masella + et al.

doi: 10.1038/nature20788

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神経科学: 時間的および空間的パターン形成の統合により神経の多様性が生まれる

Integration of temporal and spatial patterning generates neural diversity p.365

Ted Erclik, Xin Li, Maximilien Courgeon, Claire Bertet, Zhenqing Chen, Ryan Baumert, June Ng, Clara Koo, Urfa Arain, Rudy Behnia + et al.

doi: 10.1038/nature20794

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分子生物学: 5′キャップでのm6Am可逆的メチル化はmRNAの安定性を制御する

Reversible methylation of m6Am in the 5′ cap controls mRNA stability p.371

Fat mass and obesity-associated protein (FTO) preferentially demethylates m6Am, a modified adenosine that, when present at the 5′ end of certain mRNAs, positively influences mRNA stability by preventing DCP2-mediated decapping.

Jan Mauer, Xiaobing Luo, Alexandre Blanjoie, Xinfu Jiao, Anya V. Grozhik, Deepak P. Patil, Bastian Linder, Brian F. Pickering, Jean-Jacques Vasseur, Qiuying Chen + et al.

doi: 10.1038/nature21022

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分子生物学: 5′キャップでのm6Am可逆的メチル化はmRNAの安定性を制御する

Reversible methylation of m6Am in the 5′ cap controls mRNA stability p.371

doi: 10.1038/JNature7637af-5

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量子光学: サブサイクル量子電磁力学

Subcycle quantum electrodynamics p.376

C. Riek, P. Sulzer, M. Seeger, A. S. Moskalenko, G. Burkard, D. V. Seletskiy & A. Leitenstorfer

doi: 10.1038/nature21024

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化学: 速度論的にE-選択的な大環状閉環メタセシス

Kinetically E-selective macrocyclic ring-closing metathesis p.380

Xiao Shen, Thach T. Nguyen, Ming Joo Koh, Dongmin Xu, Alexander W. H. Speed, Richard R. Schrock & Amir H. Hoveyda

doi: 10.1038/nature20800

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生物地球化学: 全球的なリン循環の変化

Evolution of the global phosphorus cycle p.386

Christopher T. Reinhard, Noah J. Planavsky, Benjamin C. Gill, Kazumi Ozaki, Leslie J. Robbins, Timothy W. Lyons, Woodward W. Fischer, Chunjiang Wang, Devon B. Cole & Kurt O. Konhauser

doi: 10.1038/nature20772

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気候科学: ハリケーン活動が活発な期間に抑制される米国沿岸部に沿ったハリケーンの強化

Hurricane intensification along United States coast suppressed during active hurricane periods p.390

James P. Kossin

doi: 10.1038/nature20783

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進化学: ヒオリテス類は古生代の触手冠動物である

Hyoliths are Palaeozoic lophophorates p.394

Joseph Moysiuk, Martin R. Smith & Jean-Bernard Caron

doi: 10.1038/nature20804

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生態学: マルチスケールの規則的な植生パターンに関する理論的基盤

A theoretical foundation for multi-scale regular vegetation patterns p.398

Corina E. Tarnita, Juan A. Bonachela, Efrat Sheffer, Jennifer A. Guyton, Tyler C. Coverdale, Ryan A. Long & Robert M. Pringle

doi: 10.1038/nature20801

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遺伝学: 胚発生過程での発現レベルとアイソフォームの多様性を調節する遺伝的バリアント

Genetic variants regulating expression levels and isoform diversity during embryogenesis p.402

Enrico Cannavò, Nils Koelling, Dermot Harnett, David Garfield, Francesco P. Casale, Lucia Ciglar, Hilary E. Gustafson, Rebecca R. Viales, Raquel Marco-Ferreres, Jacob F. Degner + et al.

doi: 10.1038/nature20802

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微生物学: ヒト腸内微生物相を構成する主要な菌による栄養獲得の構造基盤

Structural basis for nutrient acquisition by dominant members of the human gut microbiota p.407

Amy J. Glenwright, Karunakar R. Pothula, Satya P. Bhamidimarri, Dror S. Chorev, Arnaud Baslé, Susan J. Firbank, Hongjun Zheng, Carol V. Robinson, Mathias Winterhalter, Ulrich Kleinekathöfer + et al.

doi: 10.1038/nature20828

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ウイルス学: PLA2G16はピコルナウイルスの侵入と排除を切り替えるスイッチである

PLA2G16 represents a switch between entry and clearance of Picornaviridae p.412

Jacqueline Staring, Eleonore von Castelmur, Vincent A. Blomen, Lisa G. van den Hengel, Markus Brockmann, Jim Baggen, Hendrik Jan Thibaut, Joppe Nieuwenhuis, Hans Janssen, Frank J. M. van Kuppeveld + et al.

doi: 10.1038/nature21032

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細胞生物学: 微小環境のオートファジーが腫瘍増殖を促進する

Microenvironmental autophagy promotes tumour growth p.417

Nadja S. Katheder, Rojyar Khezri, Fergal O’Farrell, Sebastian W. Schultz, Ashish Jain, Mohammed M. Rahman, Kay O. Schink, Theodossis A. Theodossiou, Terje Johansen, Gábor Juhász + et al.

doi: 10.1038/nature20815

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生物物理学: 界面の脂質が膜タンパク質オリゴマーの安定化に果たす役割

The role of interfacial lipids in stabilizing membrane protein oligomers p.421

Kallol Gupta, Joseph A. C. Donlan, Jonathan T. S. Hopper, Povilas Uzdavinys, Michael Landreh, Weston B. Struwe, David Drew, Andrew J. Baldwin, Phillip J. Stansfeld & Carol V. Robinson

doi: 10.1038/nature20820

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