Genetic variants associated with schizophrenia are reported this week in Nature Genetics. The findings suggest that one genetic influence in the development of schizophrenia is the dysregulation of neuronal development.
Pablo Gejman and colleagues from The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium report meta-analyses of seventeen population-based genome-wide association studies, including 21,856 individuals, for schizophrenia. They replicate their findings in an additional 29,839 individuals. They identify five genomic loci newly associated with schizophrenia.