This issue covers some of the hottest topics in stem-cell research. A News and Views article discusses the discovery that induced pluripotent stem (iPS) cells can be immunogenic. Other research articles identify an immune-privileged site in bone-marrow stem cells; a new pathway for the generation of haematopoietic stem cells; and a replacement iPS-cell inducing transcription factor for the cancer-causing c-Myc. And an article published online has identified a peptide that can stimulate progenitor cells to act as a source of new cardiomyocytes.
- Immunogenicity of induced pluripotent stem cells (Letter p212, doi: 10.1038/nature10135)
- In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche (Letter p216, doi: 10.1038/nature10160)
- A somitic Wnt16/Notch pathway specifies haematopoietic stem cells (Letter p220, doi: 10.1038/nature10107)
- Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1 (Letter p225, doi: 10.1038/nature10106)
- (News & Views p165, doi: 10.1038/474165a)
Recent Hot Topics
Sign up for Nature Research e-alerts to get the lastest research in your inbox every week.