| 1984〜1993 | Research Scientist, Software Engineering Laboratory, NEC Corporation, Tokyo, Japan |
| 1988〜1994 | Visiting Researcher, Center for Machine Translation, Carnegie Mellon University, Pittsburgh, PA, USA |
| 1993〜1996 | Researcher, Sony Computer Science Laboratories, Inc., Tokyo, Japan |
| 1996〜2002 | Senior Researcher, Sony Computer Science Laboratories, Inc., Tokyo, Japan |
| 1997〜2000 | Visiting Associate Professor, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan |
| 1997〜2002 | President, The RoboCup Federation |
| 1998〜2003 | Project Director, ERATO Kitano Symbiotic Systems Project, Japan Science and Technology Corporation, Tokyo, Japan |
| 1998〜2001 | Visiting Professor, National Institute of Genetics, Mishima, Japan |
| 2000〜 | Visiting Professor, Life Science, Keio University, Yokohama, Japan |
| 2001〜 | President, The Systems Biology Institute, Tokyo, Japan |
| 2002〜 | Director, Sony Computer Science Laboratories, Inc., Tokyo, Japan |
| 2002〜 | Founding President, The RoboCup Federation |
| 2003〜2008 | Project Director, ERATO-SORST Kitano Symbiotic Systems Project, Japan Science and Technology Agency, Tokyo, Japan |
| 2005〜2008 | Special Advisor, Okinawa Institute of Science and Technolgoy, Okinawa, Japan |
| 2006〜 | Director, Division of Cancer Systems Biology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan |
| 2007〜 | Board Member, Koozyt Inc., Tokyo, Japan |
| 2008〜 | Principal Investigator, Open Biology Unit, Okinawa Institute of Science and Technology, Okinawa, Japan |