A genetic susceptibility locus for follicular lymphoma
Nature Genetics
July 21, 2009
A common genetic variant is associated with risk for follicular lymphoma (FL), according to a study published online in this week's Nature Genetics.
Lymphomas are cancers that arise in immune system cells, and are classified into two different types: Hodgkin and non-Hodgkin lymphoma (NHL). The risk of developing NHL increases with age, and about 1 out of 4 cases of NHL is follicular lymphoma. The overall survival rate of FL varies widely, but about 20% of cases die early in the course of the disease.
In this study, Christine Skibola and colleagues analyzed the genomes of thousands of individuals with NHL. They report that a genetic variant on chromosome 6p21 is significantly associated with FL.
doi: 10.1038/ng.419
Research highlights
-
Sep 20
Cell biology: Endocannabinoid system may be involved in human testis physiologyScientific Reports
-
Sep 19
Health: Birth mode linked to microbiome disruptionNature
-
Sep 18
Ecology: Stress-resistant corals maintain heat tolerance under cooler temperaturesNature Communications
-
Sep 12
Stem cells: Modelling early human embryo developmentNature
-
Sep 11
Zoology: New electric eel species produces quite a shockNature Communications
-
Sep 11
Evolution: A virtual skull of modern humans’ last common ancestorNature Communications
