Research highlight

Risk variant for male breast cancer

Nature Genetics

September 24, 2012

The first genome-wide association study of male breast cancer, which accounts for one percent of all breast cancer cases, is reported online this week in Nature Genetics.

Nick Orr and colleagues analyze the genomes of 1,261 males of European ancestry with breast cancer. The scientists identified a variant in the gene RAD51B that is significantly associated with risk of breast cancer in men. Interestingly, RAD51B has previously been associated with risk of breast cancer in females.

doi: 10.1038/ng.2417

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