Immunology Articles

Editorial: A libelous state of affairs

The archaic nature of English libel law and its pernicious effect on scientific and medical reporting is widely criticized. Despite some recent positive developments, the situation remains perilous.

Nature Immunology, vol. 11 #9, pp767-767

News and Views: The complement receptor CD46 tips the scales in TH1 self-control

The mechanisms driving IL-10 production by human T helper type 1 effector cells are poorly defined. New data link the complement regulator protein CD46 to this process and suggest an important role in autoimmune arthritis.

Nature Immunology, vol. 11 #9, pp775-777

News and Views: All GOD's creatures got dedicated mucosal immunity

Mucosal IgA regulates the composition of gut microbiota. IgT in bony fish is now shown to have?via convergent evolution?the same properties as IgA, demonstrating strong evolutionary pressure to preserve both systemic and mucosal immunity.

Nature Immunology, vol. 11 #9, pp777-779

News and Views: A toxin-sensitive receptor able to reduce immunopathology

Immunohomeostasis prevents pathology resulting from immune activation. Two new studies link its regulation with the activation of the aryl hydrocarbon receptor, a known mediator of the toxic effects of xenobiotic ligands, in a subset of T lymphocytes.

Nature Immunology, vol. 11 #9, pp779-781

News and Views: Innate sensing of nickel

Although nickel allergy is very common, the specific receptor for nickel has not been identified. TLR4 is now shown to bind nickel and cause inflammation, an interaction that is specific to humans.

Nature Immunology, vol. 11 #9, pp781-782



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