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last updated April 2013

Institution Archive: Institute For Virus Research Kyoto University

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2013 : Institute For Virus Research Kyoto University

  • Deciphering a complex message

    Institute for Virus Research Kyoto University

    By switching off production of a key immune receptor in a specific subset of cells, researchers gain a better perspective of its numerous functions

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2012 : Institute For Virus Research Kyoto University

  • Hijacking the nucleus

    Institute for Virus Research Kyoto University

    Borna disease virus infects and remains in the nucleus of host cells by binding to the cell’s DNA scaffolding proteins

  • The long and the short of RNA export

    Institute for Virus Research Kyoto University

    A protein complex that selectively binds long RNA strands ensures that different classes of RNA molecules reach the correct destination

  • Managing the great cell divide

    Institute for Virus Research Kyoto University

    A massive screen of enzymes reveals a pathway that helps ensure that dividing cells each receive their fair share of chromosomes

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2011 : Institute For Virus Research Kyoto University

  • Clearing away peptide scraps

    Institute for Virus Research Kyoto University

    An enzyme associated with bacterial protein secretion helps clean up the peptide fragments that remain in the cell membrane after processing

  • Taking advantage of mixed messages

    Institute for Virus Research Kyoto University

    Two different patterns of signaling activity intersect to yield a precisely defined embryonic structure

  • Keeping time during development

    Institute for Virus Research Kyoto University

    Non-coding sequences called introns within a key gene help make a molecular clock tick properly during development

  • Dampening diabetes

    Institute for Virus Research Kyoto University

    Obese mice exhibit improved regulation of blood glucose levels when they lack expression of a nuclear protein that affects insulin secretion

  • Unearthing the road to resistance

    Institute for Virus Research Kyoto University

    Leukemia resistance to a common treatment is caused by loss of expression of the protein TBP-2

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2010 : Institute For Virus Research Kyoto University

  • Protective markings

    Institute for Virus Research Kyoto University

    Rapid antiviral response depends on enzymatic modification of a protein that helps activate the immune system

  • Dialing up diabetes

    Institute for Virus Research Kyoto University

    Discovery of a mechanism that triggers inflammation in patients with type 2 diabetes could lead to a new type of treatment

  • Maintaining the silence

    Institute for Virus Research Kyoto University

    The enzyme ESET prevents the expression of endogenous retroviruses to preserve the integrity of the mammalian genome

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2009 : Institute For Virus Research Kyoto University

  • Directing specialization

    Institute for Virus Research Kyoto University

    Fluorescent and luminescent reporter genes shed light on how fluctuating concentrations of a regulatory protein control the fate of cells

  • Taking out the garbage

    Institute for Virus Research Kyoto University

    When structural flaws threaten the operation of the cell’s protein-building machinery, two proteins help provide damage control

  • By invitation only

    Institute for Virus Research Kyoto University

    A chromosome-binding protein with diverse interacting partners receives its functional instructions via specific chemical modifications

  • A dual mechanism for silencing genes

    Institute for Virus Research Kyoto University

    Researchers have discovered a new way in which certain genes can be silenced in mammals

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2008 : Institute For Virus Research Kyoto University

  • Directing protein traffic

    Institute for Virus Research Kyoto University

    The crystal structure of a protein-conducting channel from a bacterium casts new light on how proteins cross cell membranes

  • A need for neurogenesis

    Institute for Virus Research Kyoto University

    Neurogenesis is required for memory formation in the hippocampus, but not in the olfactory bulb, during adulthood.

  • How oscillation keeps neural cells young

    Institute for Virus Research Kyoto University

    Cycling genes ensure the right mix of neurons in the brain

     

  • Free-range enzyme

    Institute for Virus Research Kyoto University

    A genetically influential enzyme works more liberally than previously thought

  • Unwinding a sensor of virus infection

    Institute for Virus Research Kyoto University

    Japanese researchers provide insights into the biophysical properties of a critical protein for viral immunity

  • New insight into the control of the mammalian body plan

    Institute for Virus Research Kyoto University

    Researchers identify another regulatory molecule with a key role during development

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2007 : Institute For Virus Research Kyoto University

  • Addressing messages for proper delivery

    Institute for Virus Research Kyoto University

    A recently-identified RNA sequence helps enforce cellular quality control by ensuring that only properly edited transcripts leave the nucleus

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