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last updated April 2013

Archive by Date: December 2010

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biochemical signaling: December 2010

  • Confining cancer

    Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

    Treatments that stop lung cancer cells from invading other tissues could stem from the recent identification of a critical signaling pathway

  • Reciprocal connections

    Chinese Academy of Sciences

    Odor responses in the fruit fly brain are modulated by an exchange of excitatory signals between two specific neuron populations

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cell biology: December 2010

  • Route of entry

    The Institute of Medical Science, The University of Tokyo

    The herpes virus enters host cells by binding to a myosin protein found on the cell surface

  • The acid advantage

    The University of Tokyo

    An acid-sensing receptor protein on the surface of tumor cells enhances their ability to survive and grow

  • Maintaining stem cell identity

    Genome Institute of Singapore

    Identification of the genes that keep embryonic stem cells in an undifferentiated state is an important step forward

  • Dissecting cellular crisis management

    Institute of Molecular and Cell Biology, A*STAR

    Cells rely on a complex, multi-step signal transduction pathway to coordinate their response to DNA damage

  • Cell-cycle blockers

    National Institute of Biological Sciences, Beijing

    The mechanism used by two pathogenic bacterial species to block the division of their host cells is no longer a mystery

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development: December 2010

  • Benefitting from mixed messages

    Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

    Cross-talk between two signaling pathways ensures proper development of the nervous system within a developing embryo

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genetics and evolution: December 2010

  • Getting at the roots of cancer risk

    Sun Yat-sen University Cancer Center

    Genomic analysis reveals novel risk factors for a throat cancer with elevated prevalence throughout much of Asia

  • Diversity in the genome

    The Institute of Medical Science, The University of Tokyo

    The first Japanese genome reveals the extent of human genetic variation

  • Lung cancer link

    The Institute of Medical Science, The University of Tokyo

    A newly identified genetic variant is associated with increased lung cancer risk in East Asians

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immunology: December 2010

  • Single protein seeks mature partner

    Institute for Molecular Bioscience, The University of Queensland

    Structural analysis reveals details of an important safeguard mechanism for proper immune system development

  • Fighting the flu virus

    Academia Sinica

    A campaign of very high-throughput screening for anti-influenza compounds could lead to new treatments for flu

  • Protective markings

    Institute for Virus Research Kyoto University

    Rapid antiviral response depends on enzymatic modification of a protein that helps activate the immune system

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therapeutics: December 2010

  • Cellular stress protection

    Academia Sinica

    Insights into the physiological function of a membrane transport protein may explain the mechanism underpinning a human vascular disease

  • Slow and steady

    National Institute of Immunology

    A single injection of a large insulin aggregate into diabetic animals can allow for long-term regulation of their blood glucose levels

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transcription and RNA processing: December 2010

  • Compatible partners

    National Center for Genetic Engineering and Biotechnology (BIOTEC)

    Optimal enzyme activity for viral replication of a pandemic swine-flu virus hinges on the enzyme’s subunit origins

  • Putting injured cells to sleep

    Institute of Molecular and Cell Biology, A*STAR

    A DNA damage response pathway brings cell division to a halt by eliminating a protein that maintains chromosomal integrity

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