16 May 2012LATEST HIGHLIGHTS
Reassuring patients with thin melanomas
Queensland Institute of Medical Research, Australia
A population-wide study of patients with thin melanomas shows 20-year survival rates of 96%
Gene copy-editing error causes cancer
Queensland Institute of Medical Research, Australia
A previously unknown mutation mechanism causes the heritable form of bowel cancer called Lynch syndrome
Energizing cancer cells
Institute of Biochemistry and Cell Biology, China
A newly identified signaling pathway controls the rate of glucose consumption in breast cancer cells
Searching for unknown enzyme targets
National Taiwan University, Taiwan
Large-scale screening reveals functional secrets about an important family of protein-modifying enzymes
Interpreting a pathogen’s blueprint
European Molecular Biology Laboratory, Germany
A structural analysis of the Ebola virus reveals important details about how its deadly viral particles assemble within infected cells
Unraveling the repertoire of cell-death proteins
Walter and Eliza Hall Institute of Medical Research, Australia
Proteins that regulate apoptosis also help orchestrate another cell-death mechanism called necroptosis
Protecting against Parkinson’s disease
Seoul National University, Korea
An enzyme involved in homeostasis and metabolism suppresses cell death in a fruit fly model of Parkinson’s disease
Unmasking a marker of melanoma
National Institutes of Health, USA
Whole-genome sequencing reveals a mutation that predisposes carriers to melanoma
A time and place for DNA replication
The Tokyo Metropolitan Institute of Medical Science, Japan
A screen of fission yeast mutants identifies a protein that determines when and where particular regions of the genome are copied
Managing the great cell divide
Institute for Virus Research Kyoto University, Japan
A massive screen of enzymes reveals a pathway that helps ensure that dividing cells each receive their fair share of chromosomes
Starting cancer’s ignition
Genome Institute of Singapore, Singapore
An enzyme that breaks down the amino acid glycine is linked to tumor initiation in lung cancer so may provide a new therapeutic target
Encouraging cancer-cell suicide
Seoul National University, Korea
Revelation of how a death-promoting protein acts through different receptors could improve anticancer therapeutics
